High-dimensional iterative variable selection for accelerated failure time models

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1. Verfasser: Sanyal, Nilotpal
Format: Preprint
Veröffentlicht: 2023
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author Sanyal, Nilotpal
author_facet Sanyal, Nilotpal
contents We propose an iterative variable selection method for the accelerated failure time model using high-dimensional survival data. Our method pioneers the use of the recently proposed structured screen-and-select framework for survival analysis. We use the marginal utility as the measure of association to inform the structured screening process. For the selection steps, we use Bayesian model selection based on non-local priors. We compare the proposed method with a few well-known methods. Assessment in terms of true positive rate and false discovery rate shows the usefulness of our method. We have implemented the method within the R package GWASinlps.
format Preprint
id arxiv_https___arxiv_org_abs_2304_11902
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle High-dimensional iterative variable selection for accelerated failure time models
Sanyal, Nilotpal
Methodology
We propose an iterative variable selection method for the accelerated failure time model using high-dimensional survival data. Our method pioneers the use of the recently proposed structured screen-and-select framework for survival analysis. We use the marginal utility as the measure of association to inform the structured screening process. For the selection steps, we use Bayesian model selection based on non-local priors. We compare the proposed method with a few well-known methods. Assessment in terms of true positive rate and false discovery rate shows the usefulness of our method. We have implemented the method within the R package GWASinlps.
title High-dimensional iterative variable selection for accelerated failure time models
topic Methodology
url https://arxiv.org/abs/2304.11902