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Autores principales: Bagley, Bryce Allen, Khoshnan, Navin, Petritsch, Claudia K
Formato: Preprint
Publicado: 2023
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Acceso en línea:https://arxiv.org/abs/2305.03340
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author Bagley, Bryce Allen
Khoshnan, Navin
Petritsch, Claudia K
author_facet Bagley, Bryce Allen
Khoshnan, Navin
Petritsch, Claudia K
contents As Evolutionary Dynamics moves from the realm of theory into application, algorithms are needed to move beyond simple models. Yet few such methods exist in the literature. Ecological and physiological factors are known to be central to evolution in realistic contexts, but accounting for them generally renders problems intractable to existing methods. We introduce a formulation of evolutionary games which accounts for ecology and physiology by modeling both as computations and use this to analyze the problem of directed evolution via methods from Reinforcement Learning. This combination enables us to develop first-of-their-kind results on the algorithmic problem of learning to control an evolving population of cells. We prove a complexity bound on eco-evolutionary control in situations with limited prior knowledge of cellular physiology or ecology, give the first results on the most general version of the mathematical problem of directed evolution, and establish a new link between AI and biology.
format Preprint
id arxiv_https___arxiv_org_abs_2305_03340
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Reinforcement Learning for Control of Evolutionary and Ecological Processes
Bagley, Bryce Allen
Khoshnan, Navin
Petritsch, Claudia K
Populations and Evolution
Artificial Intelligence
Systems and Control
Biological Physics
93 (Primary) 68Txx, 92Dxx, 92Cxx (Secondary)
F.2; I.2; J.2; J.3
As Evolutionary Dynamics moves from the realm of theory into application, algorithms are needed to move beyond simple models. Yet few such methods exist in the literature. Ecological and physiological factors are known to be central to evolution in realistic contexts, but accounting for them generally renders problems intractable to existing methods. We introduce a formulation of evolutionary games which accounts for ecology and physiology by modeling both as computations and use this to analyze the problem of directed evolution via methods from Reinforcement Learning. This combination enables us to develop first-of-their-kind results on the algorithmic problem of learning to control an evolving population of cells. We prove a complexity bound on eco-evolutionary control in situations with limited prior knowledge of cellular physiology or ecology, give the first results on the most general version of the mathematical problem of directed evolution, and establish a new link between AI and biology.
title Reinforcement Learning for Control of Evolutionary and Ecological Processes
topic Populations and Evolution
Artificial Intelligence
Systems and Control
Biological Physics
93 (Primary) 68Txx, 92Dxx, 92Cxx (Secondary)
F.2; I.2; J.2; J.3
url https://arxiv.org/abs/2305.03340