A Platform for the Biomedical Application of Large Language Models

Fuente: arXiv
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Autores principales: Lobentanzer, Sebastian, Feng, Shaohong, Consortium, The BioChatter, Maier, Andreas, Wang, Cankun, Baumbach, Jan, Krehl, Nils, Ma, Qin, Saez-Rodriguez, Julio
Formato: Preprint
Publicado: 2023
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author Lobentanzer, Sebastian
Feng, Shaohong
Consortium, The BioChatter
Maier, Andreas
Wang, Cankun
Baumbach, Jan
Krehl, Nils
Ma, Qin
Saez-Rodriguez, Julio
author_facet Lobentanzer, Sebastian
Feng, Shaohong
Consortium, The BioChatter
Maier, Andreas
Wang, Cankun
Baumbach, Jan
Krehl, Nils
Ma, Qin
Saez-Rodriguez, Julio
contents Current-generation Large Language Models (LLMs) have stirred enormous interest in recent months, yielding great potential for accessibility and automation, while simultaneously posing significant challenges and risk of misuse. To facilitate interfacing with LLMs in the biomedical space, while at the same time safeguarding their functionalities through sensible constraints, we propose a dedicated, open-source framework: BioChatter. Based on open-source software packages, we synergise the many functionalities that are currently developing around LLMs, such as knowledge integration / retrieval-augmented generation, model chaining, and benchmarking, resulting in an easy-to-use and inclusive framework for application in many use cases of biomedicine. We focus on robust and user-friendly implementation, including ways to deploy privacy-preserving local open-source LLMs. We demonstrate use cases via two multi-purpose web apps (https://chat.biocypher.org), and provide documentation, support, and an open community.
format Preprint
id arxiv_https___arxiv_org_abs_2305_06488
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle A Platform for the Biomedical Application of Large Language Models
Lobentanzer, Sebastian
Feng, Shaohong
Consortium, The BioChatter
Maier, Andreas
Wang, Cankun
Baumbach, Jan
Krehl, Nils
Ma, Qin
Saez-Rodriguez, Julio
Quantitative Methods
Current-generation Large Language Models (LLMs) have stirred enormous interest in recent months, yielding great potential for accessibility and automation, while simultaneously posing significant challenges and risk of misuse. To facilitate interfacing with LLMs in the biomedical space, while at the same time safeguarding their functionalities through sensible constraints, we propose a dedicated, open-source framework: BioChatter. Based on open-source software packages, we synergise the many functionalities that are currently developing around LLMs, such as knowledge integration / retrieval-augmented generation, model chaining, and benchmarking, resulting in an easy-to-use and inclusive framework for application in many use cases of biomedicine. We focus on robust and user-friendly implementation, including ways to deploy privacy-preserving local open-source LLMs. We demonstrate use cases via two multi-purpose web apps (https://chat.biocypher.org), and provide documentation, support, and an open community.
title A Platform for the Biomedical Application of Large Language Models
topic Quantitative Methods
url https://arxiv.org/abs/2305.06488