Beware of diffusion models for synthesizing medical images -- A comparison with GANs in terms of memorizing brain MRI and chest x-ray images

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Autori principali: Akbar, Muhammad Usman, Wang, Wuhao, Eklund, Anders
Natura: Preprint
Pubblicazione: 2023
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author Akbar, Muhammad Usman
Wang, Wuhao
Eklund, Anders
author_facet Akbar, Muhammad Usman
Wang, Wuhao
Eklund, Anders
contents Diffusion models were initially developed for text-to-image generation and are now being utilized to generate high quality synthetic images. Preceded by GANs, diffusion models have shown impressive results using various evaluation metrics. However, commonly used metrics such as FID and IS are not suitable for determining whether diffusion models are simply reproducing the training images. Here we train StyleGAN and a diffusion model, using BRATS20, BRATS21 and a chest x-ray pneumonia dataset, to synthesize brain MRI and chest x-ray images, and measure the correlation between the synthetic images and all training images. Our results show that diffusion models are more likely to memorize the training images, compared to StyleGAN, especially for small datasets and when using 2D slices from 3D volumes. Researchers should be careful when using diffusion models (and to some extent GANs) for medical imaging, if the final goal is to share the synthetic images.
format Preprint
id arxiv_https___arxiv_org_abs_2305_07644
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Beware of diffusion models for synthesizing medical images -- A comparison with GANs in terms of memorizing brain MRI and chest x-ray images
Akbar, Muhammad Usman
Wang, Wuhao
Eklund, Anders
Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
Diffusion models were initially developed for text-to-image generation and are now being utilized to generate high quality synthetic images. Preceded by GANs, diffusion models have shown impressive results using various evaluation metrics. However, commonly used metrics such as FID and IS are not suitable for determining whether diffusion models are simply reproducing the training images. Here we train StyleGAN and a diffusion model, using BRATS20, BRATS21 and a chest x-ray pneumonia dataset, to synthesize brain MRI and chest x-ray images, and measure the correlation between the synthetic images and all training images. Our results show that diffusion models are more likely to memorize the training images, compared to StyleGAN, especially for small datasets and when using 2D slices from 3D volumes. Researchers should be careful when using diffusion models (and to some extent GANs) for medical imaging, if the final goal is to share the synthetic images.
title Beware of diffusion models for synthesizing medical images -- A comparison with GANs in terms of memorizing brain MRI and chest x-ray images
topic Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2305.07644