The Deep Promotion Time Cure Model

Fuente: arXiv
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Hauptverfasser: Medina-Olivares, Victor, Lessmann, Stefan, Klein, Nadja
Format: Preprint
Veröffentlicht: 2023
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author Medina-Olivares, Victor
Lessmann, Stefan
Klein, Nadja
author_facet Medina-Olivares, Victor
Lessmann, Stefan
Klein, Nadja
contents We propose a novel method for predicting time-to-event in the presence of cure fractions based on flexible survivals models integrated into a deep neural network framework. Our approach allows for non-linear relationships and high-dimensional interactions between covariates and survival and is suitable for large-scale applications. Furthermore, we allow the method to incorporate an identified predictor formed of an additive decomposition of interpretable linear and non-linear effects and add an orthogonalization layer to capture potential higher dimensional interactions. We demonstrate the usefulness and computational efficiency of our method via simulations and apply it to a large portfolio of US mortgage loans. Here, we find not only a better predictive performance of our framework but also a more realistic picture of covariate effects.
format Preprint
id arxiv_https___arxiv_org_abs_2305_11575
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle The Deep Promotion Time Cure Model
Medina-Olivares, Victor
Lessmann, Stefan
Klein, Nadja
Machine Learning
We propose a novel method for predicting time-to-event in the presence of cure fractions based on flexible survivals models integrated into a deep neural network framework. Our approach allows for non-linear relationships and high-dimensional interactions between covariates and survival and is suitable for large-scale applications. Furthermore, we allow the method to incorporate an identified predictor formed of an additive decomposition of interpretable linear and non-linear effects and add an orthogonalization layer to capture potential higher dimensional interactions. We demonstrate the usefulness and computational efficiency of our method via simulations and apply it to a large portfolio of US mortgage loans. Here, we find not only a better predictive performance of our framework but also a more realistic picture of covariate effects.
title The Deep Promotion Time Cure Model
topic Machine Learning
url https://arxiv.org/abs/2305.11575