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| Format: | Preprint |
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2023
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| Online Access: | https://arxiv.org/abs/2305.14190 |
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| _version_ | 1866914642822955008 |
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| author | Ahmadianyazdi, Alireza Miller, Isaac J. Folch, Albert |
| author_facet | Ahmadianyazdi, Alireza Miller, Isaac J. Folch, Albert |
| contents | Stereolithographic 3D-printing (SLA) permits facile fabrication of high-precision microfluidic and lab-on-a-chip devices. SLA photopolymers often yield parts with low mechanical compliancy in sharp contrast to elastomers such as poly(dimethyl siloxane) (PDMS). On the other hand, SLA-printable elastomers with soft mechanical properties do not fulfill the distinct requirements for a highly manufacturable resin in microfluidics (e.g., high-resolution printability, transparency, low-viscosity). These limitations restrict our ability to print microfluidic actuators containing dynamic, movable elements. Here we introduce low-viscous photopolymers based on a tunable blend of poly(ethylene glycol) diacrylate (PEGDA, Mw~258) and poly(ethylene glycol methyl ether) methacrylate (PEGMEMA, Mw~300) monomers. In these blends, which we term PEGDA-co-PEGMEMA, tuning the PEGMEMA-to-PEGDA ratio alters the elastic modulus of the printed plastics by ~400-fold, reaching that of PDMS. Through the addition of PEGMEMA, moreover, PEGDA-co-PEGMEMA retains desirable properties of highly manufacturable PEGDA such as low viscosity, solvent compatibility, cytocompatibility and low drug absorptivity. With PEGDA-co-PEGMEMA, we SLA-printed drastically enhanced fluidic actuators including microvalves, micropumps, and microregulators with a hybrid structure containing a flexible PEGDA-co-PEGMEMA membrane within a rigid PEGDA housing. These components were built using a custom "Print-Pause-Print" protocol, referred to as "3P-printing", that allows for fabricating high-resolution multimaterial parts with a desktop SLA printer without the need for post-assembly. SLA-printing of multimaterial microfluidic actuators addresses the unmet need of high-performance on-chip controls in 3D-printed microfluidic and lab-on-a-chip devices. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2305_14190 |
| institution | arXiv |
| publishDate | 2023 |
| record_format | arxiv |
| spellingShingle | Tunable Resins with PDMS-like Elastic Modulus for Stereolithographic 3D-printing of Multimaterial Microfluidic Actuators Ahmadianyazdi, Alireza Miller, Isaac J. Folch, Albert Materials Science Chemical Physics Stereolithographic 3D-printing (SLA) permits facile fabrication of high-precision microfluidic and lab-on-a-chip devices. SLA photopolymers often yield parts with low mechanical compliancy in sharp contrast to elastomers such as poly(dimethyl siloxane) (PDMS). On the other hand, SLA-printable elastomers with soft mechanical properties do not fulfill the distinct requirements for a highly manufacturable resin in microfluidics (e.g., high-resolution printability, transparency, low-viscosity). These limitations restrict our ability to print microfluidic actuators containing dynamic, movable elements. Here we introduce low-viscous photopolymers based on a tunable blend of poly(ethylene glycol) diacrylate (PEGDA, Mw~258) and poly(ethylene glycol methyl ether) methacrylate (PEGMEMA, Mw~300) monomers. In these blends, which we term PEGDA-co-PEGMEMA, tuning the PEGMEMA-to-PEGDA ratio alters the elastic modulus of the printed plastics by ~400-fold, reaching that of PDMS. Through the addition of PEGMEMA, moreover, PEGDA-co-PEGMEMA retains desirable properties of highly manufacturable PEGDA such as low viscosity, solvent compatibility, cytocompatibility and low drug absorptivity. With PEGDA-co-PEGMEMA, we SLA-printed drastically enhanced fluidic actuators including microvalves, micropumps, and microregulators with a hybrid structure containing a flexible PEGDA-co-PEGMEMA membrane within a rigid PEGDA housing. These components were built using a custom "Print-Pause-Print" protocol, referred to as "3P-printing", that allows for fabricating high-resolution multimaterial parts with a desktop SLA printer without the need for post-assembly. SLA-printing of multimaterial microfluidic actuators addresses the unmet need of high-performance on-chip controls in 3D-printed microfluidic and lab-on-a-chip devices. |
| title | Tunable Resins with PDMS-like Elastic Modulus for Stereolithographic 3D-printing of Multimaterial Microfluidic Actuators |
| topic | Materials Science Chemical Physics |
| url | https://arxiv.org/abs/2305.14190 |