Subpopulation-Specific Synthetic EHR for Better Mortality Prediction

Fuente: arXiv
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Autori principali: Perets, Oriel, Rappoport, Nadav
Natura: Preprint
Pubblicazione: 2023
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author Perets, Oriel
Rappoport, Nadav
author_facet Perets, Oriel
Rappoport, Nadav
contents Electronic health records (EHR) often contain different rates of representation of certain subpopulations (SP). Factors like patient demographics, clinical condition prevalence, and medical center type contribute to this underrepresentation. Consequently, when training machine learning models on such datasets, the models struggle to generalize well and perform poorly on underrepresented SPs. To address this issue, we propose a novel ensemble framework that utilizes generative models. Specifically, we train a GAN-based synthetic data generator for each SP and incorporate synthetic samples into each SP training set. Ultimately, we train SP-specific prediction models. To properly evaluate this method, we design an evaluation pipeline with 2 real-world use case datasets, queried from the MIMIC database. Our approach shows increased model performance over underrepresented SPs. Our code and models are given as supplementary and will be made available on a public repository.
format Preprint
id arxiv_https___arxiv_org_abs_2305_16363
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Subpopulation-Specific Synthetic EHR for Better Mortality Prediction
Perets, Oriel
Rappoport, Nadav
Machine Learning
Electronic health records (EHR) often contain different rates of representation of certain subpopulations (SP). Factors like patient demographics, clinical condition prevalence, and medical center type contribute to this underrepresentation. Consequently, when training machine learning models on such datasets, the models struggle to generalize well and perform poorly on underrepresented SPs. To address this issue, we propose a novel ensemble framework that utilizes generative models. Specifically, we train a GAN-based synthetic data generator for each SP and incorporate synthetic samples into each SP training set. Ultimately, we train SP-specific prediction models. To properly evaluate this method, we design an evaluation pipeline with 2 real-world use case datasets, queried from the MIMIC database. Our approach shows increased model performance over underrepresented SPs. Our code and models are given as supplementary and will be made available on a public repository.
title Subpopulation-Specific Synthetic EHR for Better Mortality Prediction
topic Machine Learning
url https://arxiv.org/abs/2305.16363