The Brain Tumor Segmentation (BraTS-METS) Challenge 2023: Brain Metastasis Segmentation on Pre-treatment MRI

Fuente: arXiv
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Autori principali: Moawad, Ahmed W., Janas, Anastasia, Baid, Ujjwal, Ramakrishnan, Divya, Saluja, Rachit, Ashraf, Nader, Maleki, Nazanin, Jekel, Leon, Yordanov, Nikolay, Fehringer, Pascal, Gkampenis, Athanasios, Amiruddin, Raisa, Manteghinejad, Amirreza, Adewole, Maruf, Albrecht, Jake, Anazodo, Udunna, Aneja, Sanjay, Anwar, Syed Muhammad, Bergquist, Timothy, Chiang, Veronica, Chung, Verena, Conte, Gian Marco, Dako, Farouk, Eddy, James, Ezhov, Ivan, Khalili, Nastaran, Farahani, Keyvan, Iglesias, Juan Eugenio, Jiang, Zhifan, Johanson, Elaine, Kazerooni, Anahita Fathi, Kofler, Florian, Krantchev, Kiril, LaBella, Dominic, Van Leemput, Koen, Li, Hongwei Bran, Linguraru, Marius George, Liu, Xinyang, Meier, Zeke, Menze, Bjoern H, Moy, Harrison, Osenberg, Klara, Piraud, Marie, Reitman, Zachary, Shinohara, Russell Takeshi, Wang, Chunhao, Wiestler, Benedikt, Wiggins, Walter, Shafique, Umber, Willms, Klara, Avesta, Arman, Bousabarah, Khaled, Chakrabarty, Satrajit, Gennaro, Nicolo, Holler, Wolfgang, Kaur, Manpreet, LaMontagne, Pamela, Lin, MingDe, Lost, Jan, Marcus, Daniel S., Maresca, Ryan, Merkaj, Sarah, Pedersen, Gabriel Cassinelli, von Reppert, Marc, Sotiras, Aristeidis, Teytelboym, Oleg, Tillmans, Niklas, Westerhoff, Malte, Youssef, Ayda, Godfrey, Devon, Floyd, Scott, Rauschecker, Andreas, Villanueva-Meyer, Javier, Pfluger, Irada, Cho, Jaeyoung, Bendszus, Martin, Brugnara, Gianluca, Cramer, Justin, Perez-Carillo, Gloria J. Guzman, Johnson, Derek R., Kam, Anthony, Kwan, Benjamin Yin Ming, Lai, Lillian, Lall, Neil U., Memon, Fatima, Krycia, Mark, Patro, Satya Narayana, Petrovic, Bojan, So, Tiffany Y., Thompson, Gerard, Wu, Lei, Schrickel, E. Brooke, Bansal, Anu, Barkhof, Frederik, Besada, Cristina, Chu, Sammy, Druzgal, Jason, Dusoi, Alexandru, Farage, Luciano, Feltrin, Fabricio, Fong, Amy, Fung, Steve H., Gray, R. Ian, Ikuta, Ichiro, Iv, Michael, Postma, Alida A., Mahajan, Amit, Joyner, David, Krumpelman, Chase, Letourneau-Guillon, Laurent, Lincoln, Christie M., Maros, Mate E., Miller, Elka, Moron, Fanny, Nimchinsky, Esther A., Ozsarlak, Ozkan, Patel, Uresh, Rohatgi, Saurabh, Saha, Atin, Sayah, Anousheh, Schwartz, Eric D., Shih, Robert, Shiroishi, Mark S., Small, Juan E., Tanwar, Manoj, Valerie, Jewels, Weinberg, Brent D., White, Matthew L., Young, Robert, Zohrabian, Vahe M., Azizova, Aynur, Bruseler, Melanie Maria Theresa, Ghonim, Mohanad, Ghonim, Mohamed, Okar, Abdullah, Pasquini, Luca, Sharifi, Yasaman, Singh, Gagandeep, Sollmann, Nico, Soumala, Theodora, Taherzadeh, Mahsa, Vollmuth, Philipp, Foltyn-Dumitru, Martha, Malhotra, Ajay, Abayazeed, Aly H., Dellepiane, Francesco, Lohmann, Philipp, Perez-Garcia, Victor M., Elhalawani, Hesham, de Verdier, Maria Correia, Al-Rubaiey, Sanaria, Armindo, Rui Duarte, Ashraf, Kholod, Asla, Moamen M., Badawy, Mohamed, Bisschop, Jeroen, Lomer, Nima Broomand, Bukatz, Jan, Chen, Jim, Cimflova, Petra, Corr, Felix, Crawley, Alexis, Deptula, Lisa, Elakhdar, Tasneem, Shawali, Islam H., Faghani, Shahriar, Frick, Alexandra, Gulati, Vaibhav, Haider, Muhammad Ammar, Hierro, Fatima, Dahl, Rasmus Holmboe, Jacobs, Sarah Maria, Hsieh, Kuang-chun Jim, Kandemirli, Sedat G., Kersting, Katharina, Kida, Laura, Kollia, Sofia, Koukoulithras, Ioannis, Li, Xiao, Abouelatta, Ahmed, Mansour, Aya, Maria-Zamfirescu, Ruxandra-Catrinel, Marsiglia, Marcela, Mateo-Camacho, Yohana Sarahi, McArthur, Mark, McDonnell, Olivia, McHugh, Maire, Moassefi, Mana, Morsi, Samah Mostafa, Munteanu, Alexander, Nandolia, Khanak K., Naqvi, Syed Raza, Nikanpour, Yalda, Alnoury, Mostafa, Nouh, Abdullah Mohamed Aly, Pappafava, Francesca, Patel, Markand D., Petrucci, Samantha, Rawie, Eric, Raymond, Scott, Roohani, Borna, Sabouhi, Sadeq, Sanchez-Garcia, Laura M., Shaked, Zoe, Suthar, Pokhraj P., Altes, Talissa, Isufi, Edvin, Dhemesh, Yaseen, Gass, Jaime, Thacker, Jonathan, Tarabishy, Abdul Rahman, Turner, Benjamin, Vacca, Sebastiano, Vilanilam, George K., Warren, Daniel, Weiss, David, Worede, Fikadu, Yousry, Sara, Lerebo, Wondwossen, Aristizabal, Alejandro, Karargyris, Alexandros, Kassem, Hasan, Pati, Sarthak, Sheller, Micah, Link, Katherine E., Calabrese, Evan, Tahon, Nourel hoda, Nada, Ayman, Velichko, Yuri S., Bakas, Spyridon, Rudie, Jeffrey D., Aboian, Mariam
Natura: Preprint
Pubblicazione: 2023
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author Moawad, Ahmed W.
Janas, Anastasia
Baid, Ujjwal
Ramakrishnan, Divya
Saluja, Rachit
Ashraf, Nader
Maleki, Nazanin
Jekel, Leon
Yordanov, Nikolay
Fehringer, Pascal
Gkampenis, Athanasios
Amiruddin, Raisa
Manteghinejad, Amirreza
Adewole, Maruf
Albrecht, Jake
Anazodo, Udunna
Aneja, Sanjay
Anwar, Syed Muhammad
Bergquist, Timothy
Chiang, Veronica
Chung, Verena
Conte, Gian Marco
Dako, Farouk
Eddy, James
Ezhov, Ivan
Khalili, Nastaran
Farahani, Keyvan
Iglesias, Juan Eugenio
Jiang, Zhifan
Johanson, Elaine
Kazerooni, Anahita Fathi
Kofler, Florian
Krantchev, Kiril
LaBella, Dominic
Van Leemput, Koen
Li, Hongwei Bran
Linguraru, Marius George
Liu, Xinyang
Meier, Zeke
Menze, Bjoern H
Moy, Harrison
Osenberg, Klara
Piraud, Marie
Reitman, Zachary
Shinohara, Russell Takeshi
Wang, Chunhao
Wiestler, Benedikt
Wiggins, Walter
Shafique, Umber
Willms, Klara
Avesta, Arman
Bousabarah, Khaled
Chakrabarty, Satrajit
Gennaro, Nicolo
Holler, Wolfgang
Kaur, Manpreet
LaMontagne, Pamela
Lin, MingDe
Lost, Jan
Marcus, Daniel S.
Maresca, Ryan
Merkaj, Sarah
Pedersen, Gabriel Cassinelli
von Reppert, Marc
Sotiras, Aristeidis
Teytelboym, Oleg
Tillmans, Niklas
Westerhoff, Malte
Youssef, Ayda
Godfrey, Devon
Floyd, Scott
Rauschecker, Andreas
Villanueva-Meyer, Javier
Pfluger, Irada
Cho, Jaeyoung
Bendszus, Martin
Brugnara, Gianluca
Cramer, Justin
Perez-Carillo, Gloria J. Guzman
Johnson, Derek R.
Kam, Anthony
Kwan, Benjamin Yin Ming
Lai, Lillian
Lall, Neil U.
Memon, Fatima
Krycia, Mark
Patro, Satya Narayana
Petrovic, Bojan
So, Tiffany Y.
Thompson, Gerard
Wu, Lei
Schrickel, E. Brooke
Bansal, Anu
Barkhof, Frederik
Besada, Cristina
Chu, Sammy
Druzgal, Jason
Dusoi, Alexandru
Farage, Luciano
Feltrin, Fabricio
Fong, Amy
Fung, Steve H.
Gray, R. Ian
Ikuta, Ichiro
Iv, Michael
Postma, Alida A.
Mahajan, Amit
Joyner, David
Krumpelman, Chase
Letourneau-Guillon, Laurent
Lincoln, Christie M.
Maros, Mate E.
Miller, Elka
Moron, Fanny
Nimchinsky, Esther A.
Ozsarlak, Ozkan
Patel, Uresh
Rohatgi, Saurabh
Saha, Atin
Sayah, Anousheh
Schwartz, Eric D.
Shih, Robert
Shiroishi, Mark S.
Small, Juan E.
Tanwar, Manoj
Valerie, Jewels
Weinberg, Brent D.
White, Matthew L.
Young, Robert
Zohrabian, Vahe M.
Azizova, Aynur
Bruseler, Melanie Maria Theresa
Ghonim, Mohanad
Ghonim, Mohamed
Okar, Abdullah
Pasquini, Luca
Sharifi, Yasaman
Singh, Gagandeep
Sollmann, Nico
Soumala, Theodora
Taherzadeh, Mahsa
Vollmuth, Philipp
Foltyn-Dumitru, Martha
Malhotra, Ajay
Abayazeed, Aly H.
Dellepiane, Francesco
Lohmann, Philipp
Perez-Garcia, Victor M.
Elhalawani, Hesham
de Verdier, Maria Correia
Al-Rubaiey, Sanaria
Armindo, Rui Duarte
Ashraf, Kholod
Asla, Moamen M.
Badawy, Mohamed
Bisschop, Jeroen
Lomer, Nima Broomand
Bukatz, Jan
Chen, Jim
Cimflova, Petra
Corr, Felix
Crawley, Alexis
Deptula, Lisa
Elakhdar, Tasneem
Shawali, Islam H.
Faghani, Shahriar
Frick, Alexandra
Gulati, Vaibhav
Haider, Muhammad Ammar
Hierro, Fatima
Dahl, Rasmus Holmboe
Jacobs, Sarah Maria
Hsieh, Kuang-chun Jim
Kandemirli, Sedat G.
Kersting, Katharina
Kida, Laura
Kollia, Sofia
Koukoulithras, Ioannis
Li, Xiao
Abouelatta, Ahmed
Mansour, Aya
Maria-Zamfirescu, Ruxandra-Catrinel
Marsiglia, Marcela
Mateo-Camacho, Yohana Sarahi
McArthur, Mark
McDonnell, Olivia
McHugh, Maire
Moassefi, Mana
Morsi, Samah Mostafa
Munteanu, Alexander
Nandolia, Khanak K.
Naqvi, Syed Raza
Nikanpour, Yalda
Alnoury, Mostafa
Nouh, Abdullah Mohamed Aly
Pappafava, Francesca
Patel, Markand D.
Petrucci, Samantha
Rawie, Eric
Raymond, Scott
Roohani, Borna
Sabouhi, Sadeq
Sanchez-Garcia, Laura M.
Shaked, Zoe
Suthar, Pokhraj P.
Altes, Talissa
Isufi, Edvin
Dhemesh, Yaseen
Gass, Jaime
Thacker, Jonathan
Tarabishy, Abdul Rahman
Turner, Benjamin
Vacca, Sebastiano
Vilanilam, George K.
Warren, Daniel
Weiss, David
Worede, Fikadu
Yousry, Sara
Lerebo, Wondwossen
Aristizabal, Alejandro
Karargyris, Alexandros
Kassem, Hasan
Pati, Sarthak
Sheller, Micah
Link, Katherine E.
Calabrese, Evan
Tahon, Nourel hoda
Nada, Ayman
Velichko, Yuri S.
Bakas, Spyridon
Rudie, Jeffrey D.
Aboian, Mariam
author_facet Moawad, Ahmed W.
Janas, Anastasia
Baid, Ujjwal
Ramakrishnan, Divya
Saluja, Rachit
Ashraf, Nader
Maleki, Nazanin
Jekel, Leon
Yordanov, Nikolay
Fehringer, Pascal
Gkampenis, Athanasios
Amiruddin, Raisa
Manteghinejad, Amirreza
Adewole, Maruf
Albrecht, Jake
Anazodo, Udunna
Aneja, Sanjay
Anwar, Syed Muhammad
Bergquist, Timothy
Chiang, Veronica
Chung, Verena
Conte, Gian Marco
Dako, Farouk
Eddy, James
Ezhov, Ivan
Khalili, Nastaran
Farahani, Keyvan
Iglesias, Juan Eugenio
Jiang, Zhifan
Johanson, Elaine
Kazerooni, Anahita Fathi
Kofler, Florian
Krantchev, Kiril
LaBella, Dominic
Van Leemput, Koen
Li, Hongwei Bran
Linguraru, Marius George
Liu, Xinyang
Meier, Zeke
Menze, Bjoern H
Moy, Harrison
Osenberg, Klara
Piraud, Marie
Reitman, Zachary
Shinohara, Russell Takeshi
Wang, Chunhao
Wiestler, Benedikt
Wiggins, Walter
Shafique, Umber
Willms, Klara
Avesta, Arman
Bousabarah, Khaled
Chakrabarty, Satrajit
Gennaro, Nicolo
Holler, Wolfgang
Kaur, Manpreet
LaMontagne, Pamela
Lin, MingDe
Lost, Jan
Marcus, Daniel S.
Maresca, Ryan
Merkaj, Sarah
Pedersen, Gabriel Cassinelli
von Reppert, Marc
Sotiras, Aristeidis
Teytelboym, Oleg
Tillmans, Niklas
Westerhoff, Malte
Youssef, Ayda
Godfrey, Devon
Floyd, Scott
Rauschecker, Andreas
Villanueva-Meyer, Javier
Pfluger, Irada
Cho, Jaeyoung
Bendszus, Martin
Brugnara, Gianluca
Cramer, Justin
Perez-Carillo, Gloria J. Guzman
Johnson, Derek R.
Kam, Anthony
Kwan, Benjamin Yin Ming
Lai, Lillian
Lall, Neil U.
Memon, Fatima
Krycia, Mark
Patro, Satya Narayana
Petrovic, Bojan
So, Tiffany Y.
Thompson, Gerard
Wu, Lei
Schrickel, E. Brooke
Bansal, Anu
Barkhof, Frederik
Besada, Cristina
Chu, Sammy
Druzgal, Jason
Dusoi, Alexandru
Farage, Luciano
Feltrin, Fabricio
Fong, Amy
Fung, Steve H.
Gray, R. Ian
Ikuta, Ichiro
Iv, Michael
Postma, Alida A.
Mahajan, Amit
Joyner, David
Krumpelman, Chase
Letourneau-Guillon, Laurent
Lincoln, Christie M.
Maros, Mate E.
Miller, Elka
Moron, Fanny
Nimchinsky, Esther A.
Ozsarlak, Ozkan
Patel, Uresh
Rohatgi, Saurabh
Saha, Atin
Sayah, Anousheh
Schwartz, Eric D.
Shih, Robert
Shiroishi, Mark S.
Small, Juan E.
Tanwar, Manoj
Valerie, Jewels
Weinberg, Brent D.
White, Matthew L.
Young, Robert
Zohrabian, Vahe M.
Azizova, Aynur
Bruseler, Melanie Maria Theresa
Ghonim, Mohanad
Ghonim, Mohamed
Okar, Abdullah
Pasquini, Luca
Sharifi, Yasaman
Singh, Gagandeep
Sollmann, Nico
Soumala, Theodora
Taherzadeh, Mahsa
Vollmuth, Philipp
Foltyn-Dumitru, Martha
Malhotra, Ajay
Abayazeed, Aly H.
Dellepiane, Francesco
Lohmann, Philipp
Perez-Garcia, Victor M.
Elhalawani, Hesham
de Verdier, Maria Correia
Al-Rubaiey, Sanaria
Armindo, Rui Duarte
Ashraf, Kholod
Asla, Moamen M.
Badawy, Mohamed
Bisschop, Jeroen
Lomer, Nima Broomand
Bukatz, Jan
Chen, Jim
Cimflova, Petra
Corr, Felix
Crawley, Alexis
Deptula, Lisa
Elakhdar, Tasneem
Shawali, Islam H.
Faghani, Shahriar
Frick, Alexandra
Gulati, Vaibhav
Haider, Muhammad Ammar
Hierro, Fatima
Dahl, Rasmus Holmboe
Jacobs, Sarah Maria
Hsieh, Kuang-chun Jim
Kandemirli, Sedat G.
Kersting, Katharina
Kida, Laura
Kollia, Sofia
Koukoulithras, Ioannis
Li, Xiao
Abouelatta, Ahmed
Mansour, Aya
Maria-Zamfirescu, Ruxandra-Catrinel
Marsiglia, Marcela
Mateo-Camacho, Yohana Sarahi
McArthur, Mark
McDonnell, Olivia
McHugh, Maire
Moassefi, Mana
Morsi, Samah Mostafa
Munteanu, Alexander
Nandolia, Khanak K.
Naqvi, Syed Raza
Nikanpour, Yalda
Alnoury, Mostafa
Nouh, Abdullah Mohamed Aly
Pappafava, Francesca
Patel, Markand D.
Petrucci, Samantha
Rawie, Eric
Raymond, Scott
Roohani, Borna
Sabouhi, Sadeq
Sanchez-Garcia, Laura M.
Shaked, Zoe
Suthar, Pokhraj P.
Altes, Talissa
Isufi, Edvin
Dhemesh, Yaseen
Gass, Jaime
Thacker, Jonathan
Tarabishy, Abdul Rahman
Turner, Benjamin
Vacca, Sebastiano
Vilanilam, George K.
Warren, Daniel
Weiss, David
Worede, Fikadu
Yousry, Sara
Lerebo, Wondwossen
Aristizabal, Alejandro
Karargyris, Alexandros
Kassem, Hasan
Pati, Sarthak
Sheller, Micah
Link, Katherine E.
Calabrese, Evan
Tahon, Nourel hoda
Nada, Ayman
Velichko, Yuri S.
Bakas, Spyridon
Rudie, Jeffrey D.
Aboian, Mariam
contents The translation of AI-generated brain metastases (BM) segmentation into clinical practice relies heavily on diverse, high-quality annotated medical imaging datasets. The BraTS-METS 2023 challenge has gained momentum for testing and benchmarking algorithms using rigorously annotated internationally compiled real-world datasets. This study presents the results of the segmentation challenge and characterizes the challenging cases that impacted the performance of the winning algorithms. Untreated brain metastases on standard anatomic MRI sequences (T1, T2, FLAIR, T1PG) from eight contributed international datasets were annotated in stepwise method: published UNET algorithms, student, neuroradiologist, final approver neuroradiologist. Segmentations were ranked based on lesion-wise Dice and Hausdorff distance (HD95) scores. False positives (FP) and false negatives (FN) were rigorously penalized, receiving a score of 0 for Dice and a fixed penalty of 374 for HD95. Eight datasets comprising 1303 studies were annotated, with 402 studies (3076 lesions) released on Synapse as publicly available datasets to challenge competitors. Additionally, 31 studies (139 lesions) were held out for validation, and 59 studies (218 lesions) were used for testing. Segmentation accuracy was measured as rank across subjects, with the winning team achieving a LesionWise mean score of 7.9. Common errors among the leading teams included false negatives for small lesions and misregistration of masks in space.The BraTS-METS 2023 challenge successfully curated well-annotated, diverse datasets and identified common errors, facilitating the translation of BM segmentation across varied clinical environments and providing personalized volumetric reports to patients undergoing BM treatment.
format Preprint
id arxiv_https___arxiv_org_abs_2306_00838
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle The Brain Tumor Segmentation (BraTS-METS) Challenge 2023: Brain Metastasis Segmentation on Pre-treatment MRI
Moawad, Ahmed W.
Janas, Anastasia
Baid, Ujjwal
Ramakrishnan, Divya
Saluja, Rachit
Ashraf, Nader
Maleki, Nazanin
Jekel, Leon
Yordanov, Nikolay
Fehringer, Pascal
Gkampenis, Athanasios
Amiruddin, Raisa
Manteghinejad, Amirreza
Adewole, Maruf
Albrecht, Jake
Anazodo, Udunna
Aneja, Sanjay
Anwar, Syed Muhammad
Bergquist, Timothy
Chiang, Veronica
Chung, Verena
Conte, Gian Marco
Dako, Farouk
Eddy, James
Ezhov, Ivan
Khalili, Nastaran
Farahani, Keyvan
Iglesias, Juan Eugenio
Jiang, Zhifan
Johanson, Elaine
Kazerooni, Anahita Fathi
Kofler, Florian
Krantchev, Kiril
LaBella, Dominic
Van Leemput, Koen
Li, Hongwei Bran
Linguraru, Marius George
Liu, Xinyang
Meier, Zeke
Menze, Bjoern H
Moy, Harrison
Osenberg, Klara
Piraud, Marie
Reitman, Zachary
Shinohara, Russell Takeshi
Wang, Chunhao
Wiestler, Benedikt
Wiggins, Walter
Shafique, Umber
Willms, Klara
Avesta, Arman
Bousabarah, Khaled
Chakrabarty, Satrajit
Gennaro, Nicolo
Holler, Wolfgang
Kaur, Manpreet
LaMontagne, Pamela
Lin, MingDe
Lost, Jan
Marcus, Daniel S.
Maresca, Ryan
Merkaj, Sarah
Pedersen, Gabriel Cassinelli
von Reppert, Marc
Sotiras, Aristeidis
Teytelboym, Oleg
Tillmans, Niklas
Westerhoff, Malte
Youssef, Ayda
Godfrey, Devon
Floyd, Scott
Rauschecker, Andreas
Villanueva-Meyer, Javier
Pfluger, Irada
Cho, Jaeyoung
Bendszus, Martin
Brugnara, Gianluca
Cramer, Justin
Perez-Carillo, Gloria J. Guzman
Johnson, Derek R.
Kam, Anthony
Kwan, Benjamin Yin Ming
Lai, Lillian
Lall, Neil U.
Memon, Fatima
Krycia, Mark
Patro, Satya Narayana
Petrovic, Bojan
So, Tiffany Y.
Thompson, Gerard
Wu, Lei
Schrickel, E. Brooke
Bansal, Anu
Barkhof, Frederik
Besada, Cristina
Chu, Sammy
Druzgal, Jason
Dusoi, Alexandru
Farage, Luciano
Feltrin, Fabricio
Fong, Amy
Fung, Steve H.
Gray, R. Ian
Ikuta, Ichiro
Iv, Michael
Postma, Alida A.
Mahajan, Amit
Joyner, David
Krumpelman, Chase
Letourneau-Guillon, Laurent
Lincoln, Christie M.
Maros, Mate E.
Miller, Elka
Moron, Fanny
Nimchinsky, Esther A.
Ozsarlak, Ozkan
Patel, Uresh
Rohatgi, Saurabh
Saha, Atin
Sayah, Anousheh
Schwartz, Eric D.
Shih, Robert
Shiroishi, Mark S.
Small, Juan E.
Tanwar, Manoj
Valerie, Jewels
Weinberg, Brent D.
White, Matthew L.
Young, Robert
Zohrabian, Vahe M.
Azizova, Aynur
Bruseler, Melanie Maria Theresa
Ghonim, Mohanad
Ghonim, Mohamed
Okar, Abdullah
Pasquini, Luca
Sharifi, Yasaman
Singh, Gagandeep
Sollmann, Nico
Soumala, Theodora
Taherzadeh, Mahsa
Vollmuth, Philipp
Foltyn-Dumitru, Martha
Malhotra, Ajay
Abayazeed, Aly H.
Dellepiane, Francesco
Lohmann, Philipp
Perez-Garcia, Victor M.
Elhalawani, Hesham
de Verdier, Maria Correia
Al-Rubaiey, Sanaria
Armindo, Rui Duarte
Ashraf, Kholod
Asla, Moamen M.
Badawy, Mohamed
Bisschop, Jeroen
Lomer, Nima Broomand
Bukatz, Jan
Chen, Jim
Cimflova, Petra
Corr, Felix
Crawley, Alexis
Deptula, Lisa
Elakhdar, Tasneem
Shawali, Islam H.
Faghani, Shahriar
Frick, Alexandra
Gulati, Vaibhav
Haider, Muhammad Ammar
Hierro, Fatima
Dahl, Rasmus Holmboe
Jacobs, Sarah Maria
Hsieh, Kuang-chun Jim
Kandemirli, Sedat G.
Kersting, Katharina
Kida, Laura
Kollia, Sofia
Koukoulithras, Ioannis
Li, Xiao
Abouelatta, Ahmed
Mansour, Aya
Maria-Zamfirescu, Ruxandra-Catrinel
Marsiglia, Marcela
Mateo-Camacho, Yohana Sarahi
McArthur, Mark
McDonnell, Olivia
McHugh, Maire
Moassefi, Mana
Morsi, Samah Mostafa
Munteanu, Alexander
Nandolia, Khanak K.
Naqvi, Syed Raza
Nikanpour, Yalda
Alnoury, Mostafa
Nouh, Abdullah Mohamed Aly
Pappafava, Francesca
Patel, Markand D.
Petrucci, Samantha
Rawie, Eric
Raymond, Scott
Roohani, Borna
Sabouhi, Sadeq
Sanchez-Garcia, Laura M.
Shaked, Zoe
Suthar, Pokhraj P.
Altes, Talissa
Isufi, Edvin
Dhemesh, Yaseen
Gass, Jaime
Thacker, Jonathan
Tarabishy, Abdul Rahman
Turner, Benjamin
Vacca, Sebastiano
Vilanilam, George K.
Warren, Daniel
Weiss, David
Worede, Fikadu
Yousry, Sara
Lerebo, Wondwossen
Aristizabal, Alejandro
Karargyris, Alexandros
Kassem, Hasan
Pati, Sarthak
Sheller, Micah
Link, Katherine E.
Calabrese, Evan
Tahon, Nourel hoda
Nada, Ayman
Velichko, Yuri S.
Bakas, Spyridon
Rudie, Jeffrey D.
Aboian, Mariam
Other Quantitative Biology
Image and Video Processing
The translation of AI-generated brain metastases (BM) segmentation into clinical practice relies heavily on diverse, high-quality annotated medical imaging datasets. The BraTS-METS 2023 challenge has gained momentum for testing and benchmarking algorithms using rigorously annotated internationally compiled real-world datasets. This study presents the results of the segmentation challenge and characterizes the challenging cases that impacted the performance of the winning algorithms. Untreated brain metastases on standard anatomic MRI sequences (T1, T2, FLAIR, T1PG) from eight contributed international datasets were annotated in stepwise method: published UNET algorithms, student, neuroradiologist, final approver neuroradiologist. Segmentations were ranked based on lesion-wise Dice and Hausdorff distance (HD95) scores. False positives (FP) and false negatives (FN) were rigorously penalized, receiving a score of 0 for Dice and a fixed penalty of 374 for HD95. Eight datasets comprising 1303 studies were annotated, with 402 studies (3076 lesions) released on Synapse as publicly available datasets to challenge competitors. Additionally, 31 studies (139 lesions) were held out for validation, and 59 studies (218 lesions) were used for testing. Segmentation accuracy was measured as rank across subjects, with the winning team achieving a LesionWise mean score of 7.9. Common errors among the leading teams included false negatives for small lesions and misregistration of masks in space.The BraTS-METS 2023 challenge successfully curated well-annotated, diverse datasets and identified common errors, facilitating the translation of BM segmentation across varied clinical environments and providing personalized volumetric reports to patients undergoing BM treatment.
title The Brain Tumor Segmentation (BraTS-METS) Challenge 2023: Brain Metastasis Segmentation on Pre-treatment MRI
topic Other Quantitative Biology
Image and Video Processing
url https://arxiv.org/abs/2306.00838