Brillouin Gain Microscopy

Fuente: arXiv
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Bibliographic Details
Main Authors: Shaashoua, Roni, Kasuker, Lir, Kishner, Mor, Levy, Tal, Rotblat, Barak, Ben-Zvi, Anat, Bilenca, Alberto
Format: Preprint
Published: 2023
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author Shaashoua, Roni
Kasuker, Lir
Kishner, Mor
Levy, Tal
Rotblat, Barak
Ben-Zvi, Anat
Bilenca, Alberto
author_facet Shaashoua, Roni
Kasuker, Lir
Kishner, Mor
Levy, Tal
Rotblat, Barak
Ben-Zvi, Anat
Bilenca, Alberto
contents Optical imaging with mechanical contrast is critical for material and biological discovery since it allows contactless light-radiation force-excitation within the sample, as opposed to traditional mechanical imaging. Whilst optical microscopy based on stimulated Brillouin scattering (SBS) enables mechanical imaging of materials and living biological systems with high spectrospatial resolution, its temporal resolution remains limited. Here, we develop Brillouin gain microscopy (BGM) with a 200-fold higher temporal resolution by detecting the Brillouin gain at a mechanically contrasting frequency in the sample with high sensitivity. Using BGM, we demonstrate mechanical imaging of materials, living organisms and cells at high spectro-spatiotemporal resolution.
format Preprint
id arxiv_https___arxiv_org_abs_2306_00889
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Brillouin Gain Microscopy
Shaashoua, Roni
Kasuker, Lir
Kishner, Mor
Levy, Tal
Rotblat, Barak
Ben-Zvi, Anat
Bilenca, Alberto
Optics
Biological Physics
Optical imaging with mechanical contrast is critical for material and biological discovery since it allows contactless light-radiation force-excitation within the sample, as opposed to traditional mechanical imaging. Whilst optical microscopy based on stimulated Brillouin scattering (SBS) enables mechanical imaging of materials and living biological systems with high spectrospatial resolution, its temporal resolution remains limited. Here, we develop Brillouin gain microscopy (BGM) with a 200-fold higher temporal resolution by detecting the Brillouin gain at a mechanically contrasting frequency in the sample with high sensitivity. Using BGM, we demonstrate mechanical imaging of materials, living organisms and cells at high spectro-spatiotemporal resolution.
title Brillouin Gain Microscopy
topic Optics
Biological Physics
url https://arxiv.org/abs/2306.00889