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| Main Authors: | , , |
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| Format: | Preprint |
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2023
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| Subjects: | |
| Online Access: | https://arxiv.org/abs/2306.04700 |
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| _version_ | 1866912318506401792 |
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| author | Li, Mengbing Stephenson, Briana Wu, Zhenke |
| author_facet | Li, Mengbing Stephenson, Briana Wu, Zhenke |
| contents | Dietary patterns synthesize multiple related diet components, which can be used by nutrition researchers to examine diet-disease relationships. Latent class models (LCMs) have been used to derive dietary patterns from dietary intake assessment, where each class profile represents the probabilities of exposure to a set of diet components. However, LCM-derived dietary patterns can exhibit strong similarities, or weak separation, resulting in numerical and inferential instabilities that challenge scientific interpretation. This issue is exacerbated in small-sized subpopulations. To address these issues, we provide a simple solution that empowers LCMs to improve dietary pattern estimation. We develop a tree-regularized Bayesian LCM that shares statistical strength between dietary patterns to make better estimates using limited data. This is achieved via a Dirichlet diffusion tree process that specifies a prior distribution for the unknown tree over classes. Dietary patterns that share proximity to one another in the tree are shrunk towards ancestral dietary patterns a priori, with the degree of shrinkage varying across pre-specified food groups. Using dietary intake data from the Hispanic Community Health Study/Study of Latinos, we apply the proposed approach to a sample of 496 US adults of South American ethnic background to identify and compare dietary patterns. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2306_04700 |
| institution | arXiv |
| publishDate | 2023 |
| record_format | arxiv |
| spellingShingle | Tree-Regularized Bayesian Latent Class Analysis for Improving Weakly Separated Dietary Pattern Subtyping in Small-Sized Subpopulations Li, Mengbing Stephenson, Briana Wu, Zhenke Methodology Dietary patterns synthesize multiple related diet components, which can be used by nutrition researchers to examine diet-disease relationships. Latent class models (LCMs) have been used to derive dietary patterns from dietary intake assessment, where each class profile represents the probabilities of exposure to a set of diet components. However, LCM-derived dietary patterns can exhibit strong similarities, or weak separation, resulting in numerical and inferential instabilities that challenge scientific interpretation. This issue is exacerbated in small-sized subpopulations. To address these issues, we provide a simple solution that empowers LCMs to improve dietary pattern estimation. We develop a tree-regularized Bayesian LCM that shares statistical strength between dietary patterns to make better estimates using limited data. This is achieved via a Dirichlet diffusion tree process that specifies a prior distribution for the unknown tree over classes. Dietary patterns that share proximity to one another in the tree are shrunk towards ancestral dietary patterns a priori, with the degree of shrinkage varying across pre-specified food groups. Using dietary intake data from the Hispanic Community Health Study/Study of Latinos, we apply the proposed approach to a sample of 496 US adults of South American ethnic background to identify and compare dietary patterns. |
| title | Tree-Regularized Bayesian Latent Class Analysis for Improving Weakly Separated Dietary Pattern Subtyping in Small-Sized Subpopulations |
| topic | Methodology |
| url | https://arxiv.org/abs/2306.04700 |