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Main Authors: Blokhuis, Alex, van Kuppeveld, Martijn, van de Weem, Daan, Pollice, Robert
Format: Preprint
Published: 2023
Subjects:
Online Access:https://arxiv.org/abs/2306.09553
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author Blokhuis, Alex
van Kuppeveld, Martijn
van de Weem, Daan
Pollice, Robert
author_facet Blokhuis, Alex
van Kuppeveld, Martijn
van de Weem, Daan
Pollice, Robert
contents Chemical systems are interpreted through the species they contain and the reactions they may undergo, i.e., their chemical reaction network (CRN). In spite of their central importance to chemistry, the structure of CRNs continues to be challenging to deduce from data. Although there exist structural laws relating species, reactions, conserved quantities and cycles, there has been limited attention to their measurable consequences. One such is the dimension of the chemical data: the number of independent reactions or equivalently independent species, which corresponds to the number of measured variables minus the number of constraints. In this paper we attempt to relate the experimentally observed dimensional features to conservation laws and underlying CRN structure. Our approach extends to any Markov model as well as many nonlinear models in statistical physics and furnishes new analytical tools to find exact solutions. In particular, we investigate the effects of species that are concealed and reactions that are irreversible. For instance, irreversible reactions can have proportional rates. The resulting reduction in degrees of freedom can be captured by the co-production law relating co-production relationships to emergent non-integer conservation laws and broken cycles. This law resolves a recent conundrum posed by a machine-discovered candidate for a non-integer conservation law, and characterizes certain types of CRN behavior. We also obtain laws that allow us to relate data dimension to network structure in cases where some species cannot be discerned or distinguished by a given analytical technique, allowing to narrow down candidate CRNs from experimental data more effectively.
format Preprint
id arxiv_https___arxiv_org_abs_2306_09553
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle On data and dimension in chemistry -- irreversibility, concealment and emergent conservation laws
Blokhuis, Alex
van Kuppeveld, Martijn
van de Weem, Daan
Pollice, Robert
Statistical Mechanics
Chemical Physics
82-02, 80A30
Chemical systems are interpreted through the species they contain and the reactions they may undergo, i.e., their chemical reaction network (CRN). In spite of their central importance to chemistry, the structure of CRNs continues to be challenging to deduce from data. Although there exist structural laws relating species, reactions, conserved quantities and cycles, there has been limited attention to their measurable consequences. One such is the dimension of the chemical data: the number of independent reactions or equivalently independent species, which corresponds to the number of measured variables minus the number of constraints. In this paper we attempt to relate the experimentally observed dimensional features to conservation laws and underlying CRN structure. Our approach extends to any Markov model as well as many nonlinear models in statistical physics and furnishes new analytical tools to find exact solutions. In particular, we investigate the effects of species that are concealed and reactions that are irreversible. For instance, irreversible reactions can have proportional rates. The resulting reduction in degrees of freedom can be captured by the co-production law relating co-production relationships to emergent non-integer conservation laws and broken cycles. This law resolves a recent conundrum posed by a machine-discovered candidate for a non-integer conservation law, and characterizes certain types of CRN behavior. We also obtain laws that allow us to relate data dimension to network structure in cases where some species cannot be discerned or distinguished by a given analytical technique, allowing to narrow down candidate CRNs from experimental data more effectively.
title On data and dimension in chemistry -- irreversibility, concealment and emergent conservation laws
topic Statistical Mechanics
Chemical Physics
82-02, 80A30
url https://arxiv.org/abs/2306.09553