Bayesian variable selection using an informed reversible jump in imaging genetics: an application to schizophrenia

Fuente: arXiv
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Autores principales: Montcho, Djidenou, Zuanetti, Daiane, Chekouo, Thierry, Milan, Luis
Formato: Preprint
Publicado: 2023
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author Montcho, Djidenou
Zuanetti, Daiane
Chekouo, Thierry
Milan, Luis
author_facet Montcho, Djidenou
Zuanetti, Daiane
Chekouo, Thierry
Milan, Luis
contents From a practical perspective, proposals are one of the main bottleneck for any Markov Chain Monte Carlo (MCMC) algorithm. This paper suggests a novel data driven or informed proposal for reversible jump MCMC for Bayesian variable selection in the context of predictive risk assessment for schizophrenia based on imaging genetic data. Given functional Magnetic Resonance Image and Single Nucleotide Polymorphisms information of healthy and people diagnosed with schizophrenia, we use a Bayesian probit model to select discriminating variables for inferential purposes, while to estimate the predictive risk, the most promising models are combined using a Bayesian model averaging scheme.
format Preprint
id arxiv_https___arxiv_org_abs_2307_01134
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Bayesian variable selection using an informed reversible jump in imaging genetics: an application to schizophrenia
Montcho, Djidenou
Zuanetti, Daiane
Chekouo, Thierry
Milan, Luis
Applications
Computation
Methodology
From a practical perspective, proposals are one of the main bottleneck for any Markov Chain Monte Carlo (MCMC) algorithm. This paper suggests a novel data driven or informed proposal for reversible jump MCMC for Bayesian variable selection in the context of predictive risk assessment for schizophrenia based on imaging genetic data. Given functional Magnetic Resonance Image and Single Nucleotide Polymorphisms information of healthy and people diagnosed with schizophrenia, we use a Bayesian probit model to select discriminating variables for inferential purposes, while to estimate the predictive risk, the most promising models are combined using a Bayesian model averaging scheme.
title Bayesian variable selection using an informed reversible jump in imaging genetics: an application to schizophrenia
topic Applications
Computation
Methodology
url https://arxiv.org/abs/2307.01134