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Auteurs principaux: Bong, Suhwan, Lee, Kwonsang, Dominici, Francesca
Format: Preprint
Publié: 2023
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Accès en ligne:https://arxiv.org/abs/2307.02331
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author Bong, Suhwan
Lee, Kwonsang
Dominici, Francesca
author_facet Bong, Suhwan
Lee, Kwonsang
Dominici, Francesca
contents Observational studies are frequently used to estimate the effect of an exposure or treatment on an outcome. To obtain an unbiased estimate of the treatment effect, it is crucial to measure the exposure accurately. A common type of exposure misclassification is recall bias, which occurs in retrospective cohort studies when study subjects may inaccurately recall their past exposure. Particularly challenging is differential recall bias in the context of self-reported binary exposures, where the bias may be directional rather than random , and its extent varies according to the outcomes experienced. This paper makes several contributions: (1) it establishes bounds for the average treatment effect (ATE) even when a validation study is not available; (2) it proposes multiple estimation methods across various strategies predicated on different assumptions; and (3) it suggests a sensitivity analysis technique to assess the robustness of the causal conclusion, incorporating insights from prior research. The effectiveness of these methods is demonstrated through simulation studies that explore various model misspecification scenarios. These approaches are then applied to investigate the effect of childhood physical abuse on mental health in adulthood.
format Preprint
id arxiv_https___arxiv_org_abs_2307_02331
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Differential recall bias in estimating treatment effects in observational studies
Bong, Suhwan
Lee, Kwonsang
Dominici, Francesca
Methodology
Observational studies are frequently used to estimate the effect of an exposure or treatment on an outcome. To obtain an unbiased estimate of the treatment effect, it is crucial to measure the exposure accurately. A common type of exposure misclassification is recall bias, which occurs in retrospective cohort studies when study subjects may inaccurately recall their past exposure. Particularly challenging is differential recall bias in the context of self-reported binary exposures, where the bias may be directional rather than random , and its extent varies according to the outcomes experienced. This paper makes several contributions: (1) it establishes bounds for the average treatment effect (ATE) even when a validation study is not available; (2) it proposes multiple estimation methods across various strategies predicated on different assumptions; and (3) it suggests a sensitivity analysis technique to assess the robustness of the causal conclusion, incorporating insights from prior research. The effectiveness of these methods is demonstrated through simulation studies that explore various model misspecification scenarios. These approaches are then applied to investigate the effect of childhood physical abuse on mental health in adulthood.
title Differential recall bias in estimating treatment effects in observational studies
topic Methodology
url https://arxiv.org/abs/2307.02331