Enhancing Super-Resolution Networks through Realistic Thick-Slice CT Simulation

Fuente: arXiv
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Autori principali: Tang, Zeyu, Xing, Xiaodan, Yang, Guang
Natura: Preprint
Pubblicazione: 2023
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author Tang, Zeyu
Xing, Xiaodan
Yang, Guang
author_facet Tang, Zeyu
Xing, Xiaodan
Yang, Guang
contents Deep learning-based Generative Models have the potential to convert low-resolution CT images into high-resolution counterparts without long acquisition times and increased radiation exposure in thin-slice CT imaging. However, procuring appropriate training data for these Super-Resolution (SR) models is challenging. Previous SR research has simulated thick-slice CT images from thin-slice CT images to create training pairs. However, these methods either rely on simplistic interpolation techniques that lack realism or sinogram reconstruction, which require the release of raw data and complex reconstruction algorithms. Thus, we introduce a simple yet realistic method to generate thick CT images from thin-slice CT images, facilitating the creation of training pairs for SR algorithms. The training pairs produced by our method closely resemble real data distributions (PSNR=49.74 vs. 40.66, p$<$0.05). A multivariate Cox regression analysis involving thick slice CT images with lung fibrosis revealed that only the radiomics features extracted using our method demonstrated a significant correlation with mortality (HR=1.19 and HR=1.14, p$<$0.005). This paper represents the first to identify and address the challenge of generating appropriate paired training data for Deep Learning-based CT SR models, which enhances the efficacy and applicability of SR models in real-world scenarios.
format Preprint
id arxiv_https___arxiv_org_abs_2307_10182
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Enhancing Super-Resolution Networks through Realistic Thick-Slice CT Simulation
Tang, Zeyu
Xing, Xiaodan
Yang, Guang
Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
Medical Physics
Deep learning-based Generative Models have the potential to convert low-resolution CT images into high-resolution counterparts without long acquisition times and increased radiation exposure in thin-slice CT imaging. However, procuring appropriate training data for these Super-Resolution (SR) models is challenging. Previous SR research has simulated thick-slice CT images from thin-slice CT images to create training pairs. However, these methods either rely on simplistic interpolation techniques that lack realism or sinogram reconstruction, which require the release of raw data and complex reconstruction algorithms. Thus, we introduce a simple yet realistic method to generate thick CT images from thin-slice CT images, facilitating the creation of training pairs for SR algorithms. The training pairs produced by our method closely resemble real data distributions (PSNR=49.74 vs. 40.66, p$<$0.05). A multivariate Cox regression analysis involving thick slice CT images with lung fibrosis revealed that only the radiomics features extracted using our method demonstrated a significant correlation with mortality (HR=1.19 and HR=1.14, p$<$0.005). This paper represents the first to identify and address the challenge of generating appropriate paired training data for Deep Learning-based CT SR models, which enhances the efficacy and applicability of SR models in real-world scenarios.
title Enhancing Super-Resolution Networks through Realistic Thick-Slice CT Simulation
topic Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
Medical Physics
url https://arxiv.org/abs/2307.10182