One for Multiple: Physics-informed Synthetic Data Boosts Generalizable Deep Learning for Fast MRI Reconstruction

Fuente: arXiv
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Main Authors: Wang, Zi, Yu, Xiaotong, Wang, Chengyan, Chen, Weibo, Wang, Jiazheng, Chu, Ying-Hua, Sun, Hongwei, Li, Rushuai, Li, Peiyong, Yang, Fan, Han, Haiwei, Kang, Taishan, Lin, Jianzhong, Yang, Chen, Chang, Shufu, Shi, Zhang, Hua, Sha, Li, Yan, Hu, Juan, Zhu, Liuhong, Zhou, Jianjun, Lin, Meijing, Guo, Jiefeng, Cai, Congbo, Chen, Zhong, Guo, Di, Yang, Guang, Qu, Xiaobo
Format: Preprint
Published: 2023
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author Wang, Zi
Yu, Xiaotong
Wang, Chengyan
Chen, Weibo
Wang, Jiazheng
Chu, Ying-Hua
Sun, Hongwei
Li, Rushuai
Li, Peiyong
Yang, Fan
Han, Haiwei
Kang, Taishan
Lin, Jianzhong
Yang, Chen
Chang, Shufu
Shi, Zhang
Hua, Sha
Li, Yan
Hu, Juan
Zhu, Liuhong
Zhou, Jianjun
Lin, Meijing
Guo, Jiefeng
Cai, Congbo
Chen, Zhong
Guo, Di
Yang, Guang
Qu, Xiaobo
author_facet Wang, Zi
Yu, Xiaotong
Wang, Chengyan
Chen, Weibo
Wang, Jiazheng
Chu, Ying-Hua
Sun, Hongwei
Li, Rushuai
Li, Peiyong
Yang, Fan
Han, Haiwei
Kang, Taishan
Lin, Jianzhong
Yang, Chen
Chang, Shufu
Shi, Zhang
Hua, Sha
Li, Yan
Hu, Juan
Zhu, Liuhong
Zhou, Jianjun
Lin, Meijing
Guo, Jiefeng
Cai, Congbo
Chen, Zhong
Guo, Di
Yang, Guang
Qu, Xiaobo
contents Magnetic resonance imaging (MRI) is a widely used radiological modality renowned for its radiation-free, comprehensive insights into the human body, facilitating medical diagnoses. However, the drawback of prolonged scan times hinders its accessibility. The k-space undersampling offers a solution, yet the resultant artifacts necessitate meticulous removal during image reconstruction. Although Deep Learning (DL) has proven effective for fast MRI image reconstruction, its broader applicability across various imaging scenarios has been constrained. Challenges include the high cost and privacy restrictions associated with acquiring large-scale, diverse training data, coupled with the inherent difficulty of addressing mismatches between training and target data in existing DL methodologies. Here, we present a novel Physics-Informed Synthetic data learning framework for Fast MRI, called PISF. PISF marks a breakthrough by enabling generalized DL for multi-scenario MRI reconstruction through a single trained model. Our approach separates the reconstruction of a 2D image into many 1D basic problems, commencing with 1D data synthesis to facilitate generalization. We demonstrate that training DL models on synthetic data, coupled with enhanced learning techniques, yields in vivo MRI reconstructions comparable to or surpassing those of models trained on matched realistic datasets, reducing the reliance on real-world MRI data by up to 96%. Additionally, PISF exhibits remarkable generalizability across multiple vendors and imaging centers. Its adaptability to diverse patient populations has been validated through evaluations by ten experienced medical professionals. PISF presents a feasible and cost-effective way to significantly boost the widespread adoption of DL in various fast MRI applications.
format Preprint
id arxiv_https___arxiv_org_abs_2307_13220
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle One for Multiple: Physics-informed Synthetic Data Boosts Generalizable Deep Learning for Fast MRI Reconstruction
Wang, Zi
Yu, Xiaotong
Wang, Chengyan
Chen, Weibo
Wang, Jiazheng
Chu, Ying-Hua
Sun, Hongwei
Li, Rushuai
Li, Peiyong
Yang, Fan
Han, Haiwei
Kang, Taishan
Lin, Jianzhong
Yang, Chen
Chang, Shufu
Shi, Zhang
Hua, Sha
Li, Yan
Hu, Juan
Zhu, Liuhong
Zhou, Jianjun
Lin, Meijing
Guo, Jiefeng
Cai, Congbo
Chen, Zhong
Guo, Di
Yang, Guang
Qu, Xiaobo
Image and Video Processing
Artificial Intelligence
Medical Physics
Magnetic resonance imaging (MRI) is a widely used radiological modality renowned for its radiation-free, comprehensive insights into the human body, facilitating medical diagnoses. However, the drawback of prolonged scan times hinders its accessibility. The k-space undersampling offers a solution, yet the resultant artifacts necessitate meticulous removal during image reconstruction. Although Deep Learning (DL) has proven effective for fast MRI image reconstruction, its broader applicability across various imaging scenarios has been constrained. Challenges include the high cost and privacy restrictions associated with acquiring large-scale, diverse training data, coupled with the inherent difficulty of addressing mismatches between training and target data in existing DL methodologies. Here, we present a novel Physics-Informed Synthetic data learning framework for Fast MRI, called PISF. PISF marks a breakthrough by enabling generalized DL for multi-scenario MRI reconstruction through a single trained model. Our approach separates the reconstruction of a 2D image into many 1D basic problems, commencing with 1D data synthesis to facilitate generalization. We demonstrate that training DL models on synthetic data, coupled with enhanced learning techniques, yields in vivo MRI reconstructions comparable to or surpassing those of models trained on matched realistic datasets, reducing the reliance on real-world MRI data by up to 96%. Additionally, PISF exhibits remarkable generalizability across multiple vendors and imaging centers. Its adaptability to diverse patient populations has been validated through evaluations by ten experienced medical professionals. PISF presents a feasible and cost-effective way to significantly boost the widespread adoption of DL in various fast MRI applications.
title One for Multiple: Physics-informed Synthetic Data Boosts Generalizable Deep Learning for Fast MRI Reconstruction
topic Image and Video Processing
Artificial Intelligence
Medical Physics
url https://arxiv.org/abs/2307.13220