Enhancing Cell Tracking with a Time-Symmetric Deep Learning Approach

Fuente: arXiv
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Hauptverfasser: Szabó, Gergely, Bonaiuti, Paolo, Ciliberto, Andrea, Horváth, András
Format: Preprint
Veröffentlicht: 2023
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author Szabó, Gergely
Bonaiuti, Paolo
Ciliberto, Andrea
Horváth, András
author_facet Szabó, Gergely
Bonaiuti, Paolo
Ciliberto, Andrea
Horváth, András
contents The accurate tracking of live cells using video microscopy recordings remains a challenging task for popular state-of-the-art image processing based object tracking methods. In recent years, several existing and new applications have attempted to integrate deep-learning based frameworks for this task, but most of them still heavily rely on consecutive frame based tracking embedded in their architecture or other premises that hinder generalized learning. To address this issue, we aimed to develop a new deep-learning based tracking method that relies solely on the assumption that cells can be tracked based on their spatio-temporal neighborhood, without restricting it to consecutive frames. The proposed method has the additional benefit that the motion patterns of the cells can be learned completely by the predictor without any prior assumptions, and it has the potential to handle a large number of video frames with heavy artifacts. The efficacy of the proposed method is demonstrated through biologically motivated validation strategies and compared against multiple state-of-the-art cell tracking methods.
format Preprint
id arxiv_https___arxiv_org_abs_2308_03887
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Enhancing Cell Tracking with a Time-Symmetric Deep Learning Approach
Szabó, Gergely
Bonaiuti, Paolo
Ciliberto, Andrea
Horváth, András
Image and Video Processing
Machine Learning
Quantitative Methods
The accurate tracking of live cells using video microscopy recordings remains a challenging task for popular state-of-the-art image processing based object tracking methods. In recent years, several existing and new applications have attempted to integrate deep-learning based frameworks for this task, but most of them still heavily rely on consecutive frame based tracking embedded in their architecture or other premises that hinder generalized learning. To address this issue, we aimed to develop a new deep-learning based tracking method that relies solely on the assumption that cells can be tracked based on their spatio-temporal neighborhood, without restricting it to consecutive frames. The proposed method has the additional benefit that the motion patterns of the cells can be learned completely by the predictor without any prior assumptions, and it has the potential to handle a large number of video frames with heavy artifacts. The efficacy of the proposed method is demonstrated through biologically motivated validation strategies and compared against multiple state-of-the-art cell tracking methods.
title Enhancing Cell Tracking with a Time-Symmetric Deep Learning Approach
topic Image and Video Processing
Machine Learning
Quantitative Methods
url https://arxiv.org/abs/2308.03887