Estimating Causal Effects for Binary Outcomes Using Per-Decision Inverse Probability Weighting

Fuente: arXiv
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Main Authors: Bao, Yihan, Bell, Lauren, Williamson, Elizabeth, Garnett, Claire, Qian, Tianchen
Format: Preprint
Published: 2023
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author Bao, Yihan
Bell, Lauren
Williamson, Elizabeth
Garnett, Claire
Qian, Tianchen
author_facet Bao, Yihan
Bell, Lauren
Williamson, Elizabeth
Garnett, Claire
Qian, Tianchen
contents Micro-randomized trials are commonly conducted for optimizing mobile health interventions such as push notifications for behavior change. In analyzing such trials, causal excursion effects are often of primary interest, and their estimation typically involves inverse probability weighting (IPW). However, in a micro-randomized trial, additional treatments can often occur during the time window over which an outcome is defined, and this can greatly inflate the variance of the causal effect estimator because IPW would involve a product of numerous weights. To reduce variance and improve estimation efficiency, we propose two new estimators using a modified version of IPW, which we call "per-decision IPW". The second estimator further improves efficiency using the projection idea from the semiparametric efficiency theory. These estimators are applicable when the outcome is binary and can be expressed as the maximum of a series of sub-outcomes defined over sub-intervals of time. We establish the estimators' consistency and asymptotic normality. Through simulation studies and real data applications, we demonstrate substantial efficiency improvement of the proposed estimator over existing estimators. The new estimators can be used to improve the precision of primary and secondary analyses for micro-randomized trials with binary outcomes.
format Preprint
id arxiv_https___arxiv_org_abs_2308_12260
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Estimating Causal Effects for Binary Outcomes Using Per-Decision Inverse Probability Weighting
Bao, Yihan
Bell, Lauren
Williamson, Elizabeth
Garnett, Claire
Qian, Tianchen
Methodology
Applications
Micro-randomized trials are commonly conducted for optimizing mobile health interventions such as push notifications for behavior change. In analyzing such trials, causal excursion effects are often of primary interest, and their estimation typically involves inverse probability weighting (IPW). However, in a micro-randomized trial, additional treatments can often occur during the time window over which an outcome is defined, and this can greatly inflate the variance of the causal effect estimator because IPW would involve a product of numerous weights. To reduce variance and improve estimation efficiency, we propose two new estimators using a modified version of IPW, which we call "per-decision IPW". The second estimator further improves efficiency using the projection idea from the semiparametric efficiency theory. These estimators are applicable when the outcome is binary and can be expressed as the maximum of a series of sub-outcomes defined over sub-intervals of time. We establish the estimators' consistency and asymptotic normality. Through simulation studies and real data applications, we demonstrate substantial efficiency improvement of the proposed estimator over existing estimators. The new estimators can be used to improve the precision of primary and secondary analyses for micro-randomized trials with binary outcomes.
title Estimating Causal Effects for Binary Outcomes Using Per-Decision Inverse Probability Weighting
topic Methodology
Applications
url https://arxiv.org/abs/2308.12260