MLN-net: A multi-source medical image segmentation method for clustered microcalcifications using multiple layer normalization

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Main Authors: Wang, Ke, Ye, Zanting, Xie, Xiang, Cui, Haidong, Chen, Tao, Liu, Banteng
Format: Preprint
Published: 2023
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author Wang, Ke
Ye, Zanting
Xie, Xiang
Cui, Haidong
Chen, Tao
Liu, Banteng
author_facet Wang, Ke
Ye, Zanting
Xie, Xiang
Cui, Haidong
Chen, Tao
Liu, Banteng
contents Accurate segmentation of clustered microcalcifications in mammography is crucial for the diagnosis and treatment of breast cancer. Despite exhibiting expert-level accuracy, recent deep learning advancements in medical image segmentation provide insufficient contribution to practical applications, due to the domain shift resulting from differences in patient postures, individual gland density, and imaging modalities of mammography etc. In this paper, a novel framework named MLN-net, which can accurately segment multi-source images using only single source images, is proposed for clustered microcalcification segmentation. We first propose a source domain image augmentation method to generate multi-source images, leading to improved generalization. And a structure of multiple layer normalization (LN) layers is used to construct the segmentation network, which can be found efficient for clustered microcalcification segmentation in different domains. Additionally, a branch selection strategy is designed for measuring the similarity of the source domain data and the target domain data. To validate the proposed MLN-net, extensive analyses including ablation experiments are performed, comparison of 12 baseline methods. Extensive experiments validate the effectiveness of MLN-net in segmenting clustered microcalcifications from different domains and the its segmentation accuracy surpasses state-of-the-art methods. Code will be available at https://github.com/yezanting/MLN-NET-VERSON1.
format Preprint
id arxiv_https___arxiv_org_abs_2309_02742
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle MLN-net: A multi-source medical image segmentation method for clustered microcalcifications using multiple layer normalization
Wang, Ke
Ye, Zanting
Xie, Xiang
Cui, Haidong
Chen, Tao
Liu, Banteng
Computer Vision and Pattern Recognition
Artificial Intelligence
Accurate segmentation of clustered microcalcifications in mammography is crucial for the diagnosis and treatment of breast cancer. Despite exhibiting expert-level accuracy, recent deep learning advancements in medical image segmentation provide insufficient contribution to practical applications, due to the domain shift resulting from differences in patient postures, individual gland density, and imaging modalities of mammography etc. In this paper, a novel framework named MLN-net, which can accurately segment multi-source images using only single source images, is proposed for clustered microcalcification segmentation. We first propose a source domain image augmentation method to generate multi-source images, leading to improved generalization. And a structure of multiple layer normalization (LN) layers is used to construct the segmentation network, which can be found efficient for clustered microcalcification segmentation in different domains. Additionally, a branch selection strategy is designed for measuring the similarity of the source domain data and the target domain data. To validate the proposed MLN-net, extensive analyses including ablation experiments are performed, comparison of 12 baseline methods. Extensive experiments validate the effectiveness of MLN-net in segmenting clustered microcalcifications from different domains and the its segmentation accuracy surpasses state-of-the-art methods. Code will be available at https://github.com/yezanting/MLN-NET-VERSON1.
title MLN-net: A multi-source medical image segmentation method for clustered microcalcifications using multiple layer normalization
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2309.02742