Subgroup detection in linear growth curve models with generalized linear mixed model (GLMM) trees

Fuente: arXiv
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Main Authors: Fokkema, Marjolein, Zeileis, Achim
Format: Preprint
Published: 2023
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author Fokkema, Marjolein
Zeileis, Achim
author_facet Fokkema, Marjolein
Zeileis, Achim
contents Growth curve models are popular tools for studying the development of a response variable within subjects over time. Heterogeneity between subjects is common in such models, and researchers are typically interested in explaining or predicting this heterogeneity. We show how generalized linear mixed effects model (GLMM) trees can be used to identify subgroups with differently shaped trajectories in linear growth curve models. Originally developed for clustered cross-sectional data, GLMM trees are extended here to longitudinal data. The resulting extended GLMM trees are directly applicable to growth curve models as an important special case. In simulated and real-world data, we assess the performance of the extensions and compare against other partitioning methods for growth curve models. Extended GLMM trees perform more accurately than the original algorithm and LongCART, and similarly accurate as structural equation model (SEM) trees. In addition, GLMM trees allow for modeling both discrete and continuous time series, are less sensitive to (mis-)specification of the random-effects structure and are much faster to compute.
format Preprint
id arxiv_https___arxiv_org_abs_2309_05862
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Subgroup detection in linear growth curve models with generalized linear mixed model (GLMM) trees
Fokkema, Marjolein
Zeileis, Achim
Methodology
Machine Learning
Growth curve models are popular tools for studying the development of a response variable within subjects over time. Heterogeneity between subjects is common in such models, and researchers are typically interested in explaining or predicting this heterogeneity. We show how generalized linear mixed effects model (GLMM) trees can be used to identify subgroups with differently shaped trajectories in linear growth curve models. Originally developed for clustered cross-sectional data, GLMM trees are extended here to longitudinal data. The resulting extended GLMM trees are directly applicable to growth curve models as an important special case. In simulated and real-world data, we assess the performance of the extensions and compare against other partitioning methods for growth curve models. Extended GLMM trees perform more accurately than the original algorithm and LongCART, and similarly accurate as structural equation model (SEM) trees. In addition, GLMM trees allow for modeling both discrete and continuous time series, are less sensitive to (mis-)specification of the random-effects structure and are much faster to compute.
title Subgroup detection in linear growth curve models with generalized linear mixed model (GLMM) trees
topic Methodology
Machine Learning
url https://arxiv.org/abs/2309.05862