Frequentist Inference for Semi-mechanistic Epidemic Models with Interventions

Fuente: arXiv
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Autores principales: Bong, Heejong, Ventura, Valérie, Wasserman, Larry
Formato: Preprint
Publicado: 2023
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author Bong, Heejong
Ventura, Valérie
Wasserman, Larry
author_facet Bong, Heejong
Ventura, Valérie
Wasserman, Larry
contents The effect of public health interventions on an epidemic are often estimated by adding the intervention to epidemic models. During the Covid-19 epidemic, numerous papers used such methods for making scenario predictions. The majority of these papers use Bayesian methods to estimate the parameters of the model. In this paper we show how to use frequentist methods for estimating these effects which avoids having to specify prior distributions. We also use model-free shrinkage methods to improve estimation when there are many different geographic regions. This allows us to borrow strength from different regions while still getting confidence intervals with correct coverage and without having to specify a hierarchical model. Throughout, we focus on a semi-mechanistic model which provides a simple, tractable alternative to compartmental methods.
format Preprint
id arxiv_https___arxiv_org_abs_2309_10792
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Frequentist Inference for Semi-mechanistic Epidemic Models with Interventions
Bong, Heejong
Ventura, Valérie
Wasserman, Larry
Methodology
Applications
The effect of public health interventions on an epidemic are often estimated by adding the intervention to epidemic models. During the Covid-19 epidemic, numerous papers used such methods for making scenario predictions. The majority of these papers use Bayesian methods to estimate the parameters of the model. In this paper we show how to use frequentist methods for estimating these effects which avoids having to specify prior distributions. We also use model-free shrinkage methods to improve estimation when there are many different geographic regions. This allows us to borrow strength from different regions while still getting confidence intervals with correct coverage and without having to specify a hierarchical model. Throughout, we focus on a semi-mechanistic model which provides a simple, tractable alternative to compartmental methods.
title Frequentist Inference for Semi-mechanistic Epidemic Models with Interventions
topic Methodology
Applications
url https://arxiv.org/abs/2309.10792