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Main Authors: Foti, Simone, Rickart, Alexander J., Koo, Bongjin, Sullivan, Eimear O', van de Lande, Lara S., Papaioannou, Athanasios, Khonsari, Roman, Stoyanov, Danail, Jeelani, N. u. Owase, Schievano, Silvia, Dunaway, David J., Clarkson, Matthew J.
Format: Preprint
Published: 2023
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Online Access:https://arxiv.org/abs/2309.10825
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author Foti, Simone
Rickart, Alexander J.
Koo, Bongjin
Sullivan, Eimear O'
van de Lande, Lara S.
Papaioannou, Athanasios
Khonsari, Roman
Stoyanov, Danail
Jeelani, N. u. Owase
Schievano, Silvia
Dunaway, David J.
Clarkson, Matthew J.
author_facet Foti, Simone
Rickart, Alexander J.
Koo, Bongjin
Sullivan, Eimear O'
van de Lande, Lara S.
Papaioannou, Athanasios
Khonsari, Roman
Stoyanov, Danail
Jeelani, N. u. Owase
Schievano, Silvia
Dunaway, David J.
Clarkson, Matthew J.
contents The use of deep learning to undertake shape analysis of the complexities of the human head holds great promise. However, there have traditionally been a number of barriers to accurate modelling, especially when operating on both a global and local level. In this work, we will discuss the application of the Swap Disentangled Variational Autoencoder (SD-VAE) with relevance to Crouzon, Apert and Muenke syndromes. Although syndrome classification is performed on the entire mesh, it is also possible, for the first time, to analyse the influence of each region of the head on the syndromic phenotype. By manipulating specific parameters of the generative model, and producing procedure-specific new shapes, it is also possible to simulate the outcome of a range of craniofacial surgical procedures. This opens new avenues to advance diagnosis, aids surgical planning and allows for the objective evaluation of surgical outcomes.
format Preprint
id arxiv_https___arxiv_org_abs_2309_10825
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Latent Disentanglement in Mesh Variational Autoencoders Improves the Diagnosis of Craniofacial Syndromes and Aids Surgical Planning
Foti, Simone
Rickart, Alexander J.
Koo, Bongjin
Sullivan, Eimear O'
van de Lande, Lara S.
Papaioannou, Athanasios
Khonsari, Roman
Stoyanov, Danail
Jeelani, N. u. Owase
Schievano, Silvia
Dunaway, David J.
Clarkson, Matthew J.
Image and Video Processing
Machine Learning
Quantitative Methods
The use of deep learning to undertake shape analysis of the complexities of the human head holds great promise. However, there have traditionally been a number of barriers to accurate modelling, especially when operating on both a global and local level. In this work, we will discuss the application of the Swap Disentangled Variational Autoencoder (SD-VAE) with relevance to Crouzon, Apert and Muenke syndromes. Although syndrome classification is performed on the entire mesh, it is also possible, for the first time, to analyse the influence of each region of the head on the syndromic phenotype. By manipulating specific parameters of the generative model, and producing procedure-specific new shapes, it is also possible to simulate the outcome of a range of craniofacial surgical procedures. This opens new avenues to advance diagnosis, aids surgical planning and allows for the objective evaluation of surgical outcomes.
title Latent Disentanglement in Mesh Variational Autoencoders Improves the Diagnosis of Craniofacial Syndromes and Aids Surgical Planning
topic Image and Video Processing
Machine Learning
Quantitative Methods
url https://arxiv.org/abs/2309.10825