HyMNet: a Multimodal Deep Learning System for Hypertension Classification using Fundus Photographs and Cardiometabolic Risk Factors

Fuente: arXiv
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Main Authors: Baharoon, Mohammed, Almatar, Hessa, Alduhayan, Reema, Aldebasi, Tariq, Alahmadi, Badr, Bokhari, Yahya, Alawad, Mohammed, Almazroa, Ahmed, Aljouie, Abdulrhman
Format: Preprint
Published: 2023
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author Baharoon, Mohammed
Almatar, Hessa
Alduhayan, Reema
Aldebasi, Tariq
Alahmadi, Badr
Bokhari, Yahya
Alawad, Mohammed
Almazroa, Ahmed
Aljouie, Abdulrhman
author_facet Baharoon, Mohammed
Almatar, Hessa
Alduhayan, Reema
Aldebasi, Tariq
Alahmadi, Badr
Bokhari, Yahya
Alawad, Mohammed
Almazroa, Ahmed
Aljouie, Abdulrhman
contents In recent years, deep learning has shown promise in predicting hypertension (HTN) from fundus images. However, most prior research has primarily focused on analyzing a single type of data, which may not capture the full complexity of HTN risk. To address this limitation, this study introduces a multimodal deep learning (MMDL) system, dubbed HyMNet, which combines fundus images and cardiometabolic risk factors, specifically age and gender, to improve hypertension detection capabilities. Our MMDL system uses RETFound, a foundation model pre-trained on 1.6 million retinal images, for the fundus path and a fully connected neural network for the age and gender path. The two paths are jointly trained by concatenating the feature vectors from each path that are then fed into a fusion network. The system was trained on 5,016 retinal images from 1,243 individuals collected from the Saudi Ministry of National Guard Health Affairs. The results show that the multimodal model that integrates fundus images along with age and gender outperforms the unimodal system trained solely on fundus photographs, with an F1 score of 0.771 [0.747, 0.796], and 0.745 [0.719, 0.772] for hypertension detection, respectively. Additionally, we studied the effect underlying diabetes mellitus has on the model's predictive ability, concluding that diabetes is used as a confounding variable for distinguishing hypertensive cases. Our code and model weights are publicly available at https://github.com/MohammedSB/HyMNet.
format Preprint
id arxiv_https___arxiv_org_abs_2310_01099
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle HyMNet: a Multimodal Deep Learning System for Hypertension Classification using Fundus Photographs and Cardiometabolic Risk Factors
Baharoon, Mohammed
Almatar, Hessa
Alduhayan, Reema
Aldebasi, Tariq
Alahmadi, Badr
Bokhari, Yahya
Alawad, Mohammed
Almazroa, Ahmed
Aljouie, Abdulrhman
Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
In recent years, deep learning has shown promise in predicting hypertension (HTN) from fundus images. However, most prior research has primarily focused on analyzing a single type of data, which may not capture the full complexity of HTN risk. To address this limitation, this study introduces a multimodal deep learning (MMDL) system, dubbed HyMNet, which combines fundus images and cardiometabolic risk factors, specifically age and gender, to improve hypertension detection capabilities. Our MMDL system uses RETFound, a foundation model pre-trained on 1.6 million retinal images, for the fundus path and a fully connected neural network for the age and gender path. The two paths are jointly trained by concatenating the feature vectors from each path that are then fed into a fusion network. The system was trained on 5,016 retinal images from 1,243 individuals collected from the Saudi Ministry of National Guard Health Affairs. The results show that the multimodal model that integrates fundus images along with age and gender outperforms the unimodal system trained solely on fundus photographs, with an F1 score of 0.771 [0.747, 0.796], and 0.745 [0.719, 0.772] for hypertension detection, respectively. Additionally, we studied the effect underlying diabetes mellitus has on the model's predictive ability, concluding that diabetes is used as a confounding variable for distinguishing hypertensive cases. Our code and model weights are publicly available at https://github.com/MohammedSB/HyMNet.
title HyMNet: a Multimodal Deep Learning System for Hypertension Classification using Fundus Photographs and Cardiometabolic Risk Factors
topic Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2310.01099