TrialView: An AI-powered Visual Analytics System for Temporal Event Data in Clinical Trials
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arXiv
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| Main Authors: | , , , , , |
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| Format: | Preprint |
| Published: |
2023
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| _version_ | 1866910310687834112 |
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| author | Li, Zuotian Liu, Xiang Cheng, Zelei Chen, Yingjie Tu, Wanzhu Su, Jing |
| author_facet | Li, Zuotian Liu, Xiang Cheng, Zelei Chen, Yingjie Tu, Wanzhu Su, Jing |
| contents | Randomized controlled trials (RCT) are the gold standards for evaluating the efficacy and safety of therapeutic interventions in human subjects. In addition to the pre-specified endpoints, trial participants' experience reveals the time course of the intervention. Few analytical tools exist to summarize and visualize the individual experience of trial participants. Visual analytics allows integrative examination of temporal event patterns of patient experience, thus generating insights for better care decisions. Towards this end, we introduce TrialView, an information system that combines graph artificial intelligence (AI) and visual analytics to enhance the dissemination of trial data. TrialView offers four distinct yet interconnected views: Individual, Cohort, Progression, and Statistics, enabling an interactive exploration of individual and group-level data. The TrialView system is a general-purpose analytical tool for a broad class of clinical trials. The system is powered by graph AI, knowledge-guided clustering, explanatory modeling, and graph-based agglomeration algorithms. We demonstrate the system's effectiveness in analyzing temporal event data through a case study. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2310_04586 |
| institution | arXiv |
| publishDate | 2023 |
| record_format | arxiv |
| spellingShingle | TrialView: An AI-powered Visual Analytics System for Temporal Event Data in Clinical Trials Li, Zuotian Liu, Xiang Cheng, Zelei Chen, Yingjie Tu, Wanzhu Su, Jing Human-Computer Interaction Randomized controlled trials (RCT) are the gold standards for evaluating the efficacy and safety of therapeutic interventions in human subjects. In addition to the pre-specified endpoints, trial participants' experience reveals the time course of the intervention. Few analytical tools exist to summarize and visualize the individual experience of trial participants. Visual analytics allows integrative examination of temporal event patterns of patient experience, thus generating insights for better care decisions. Towards this end, we introduce TrialView, an information system that combines graph artificial intelligence (AI) and visual analytics to enhance the dissemination of trial data. TrialView offers four distinct yet interconnected views: Individual, Cohort, Progression, and Statistics, enabling an interactive exploration of individual and group-level data. The TrialView system is a general-purpose analytical tool for a broad class of clinical trials. The system is powered by graph AI, knowledge-guided clustering, explanatory modeling, and graph-based agglomeration algorithms. We demonstrate the system's effectiveness in analyzing temporal event data through a case study. |
| title | TrialView: An AI-powered Visual Analytics System for Temporal Event Data in Clinical Trials |
| topic | Human-Computer Interaction |
| url | https://arxiv.org/abs/2310.04586 |