Cover Image

Assurance Methods for designing a clinical trial with a delayed treatment effect

Fuente: arXiv

Saved in:

Bibliographic Details
Main Authors:	Salsbury, James, Oakley, Jeremy, Julious, Steven, Hampson, Lisa
Format:	Preprint
Published:	2023
Subjects:	Applications Methodology
Online Access:	Acceder al recurso
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Adaptive clinical trial design with delayed treatment effects using elicited prior distributions
by: Salsbury, James, et al.
Published: (2025)

Assurance methods for designing a clinical trial with a delayed treatment effect
by: James A. Salsbury, et al.
Published: (2024)

Dose optimization design accounting for unknown patient heterogeneity in cancer clinical trials
by: Silva, Rebecca B., et al.
Published: (2025)

Generalizing conditional average treatment effects from nested randomized trials to all trial-eligible individuals
by: Wen, Lan, et al.
Published: (2026)

Estimating treatment effects with competing intercurrent events in randomized controlled trials
by: Lu, Sizhu, et al.
Published: (2025)

Using shrinkage methods to estimate treatment effects in overlapping subgroups in randomized clinical trials with a time-to-event endpoint
by: Wolbers, Marcel, et al.
Published: (2024)

The role of randomization inference in unraveling individual treatment effects in early phase vaccine trials
by: Chen, Zhe, et al.
Published: (2023)

Nonparametric estimation of an optimal treatment rule with fused randomized trials and missing effect modifiers
by: Williams, Nicholas, et al.
Published: (2025)

Rank-based estimators of global treatment effects for cluster randomized trials with multiple endpoints
by: Smith, E. Davies, et al.
Published: (2024)

Continuous monitoring of delayed outcomes in basket trials
by: Diniz, Marcio A., et al.
Published: (2026)

A comparison of methods for designing hybrid type 2 cluster-randomized trials with continuous effectiveness and implementation endpoints
by: Owen, Melody, et al.
Published: (2025)

Data-driven controlled subgroup selection in clinical trials
by: Müller, Manuel M., et al.
Published: (2025)

The R.O.A.D. to clinical trial emulation
by: Bertsimas, Dimitris, et al.
Published: (2024)

Randomization inference for stepped-wedge designs with noncompliance with application to a palliative care pragmatic trial
by: Zhang, Jeffrey, et al.
Published: (2025)

The Bayesian optimal two-stage design for clinical phase II trials based on Bayes factors
by: Kelter, Riko, et al.
Published: (2025)

Utility-based optimization of Fujikawa's basket trial design -- Pre-specified protocol of a comparison study
by: Sauer, Lukas D, et al.
Published: (2024)

Bias reduction in g-computation for covariate adjustment in randomized clinical trials
by: Zhang, Xin, et al.
Published: (2025)

Estimating average treatment effects when treatment data are absent in a target study
by: Wen, Lan, et al.
Published: (2025)

A multi-arm multi-stage design for trials with all pairwise testing
by: Greenstreet, Peter, et al.
Published: (2025)

A tutorial on conducting sample size and power calculations for detecting treatment effect heterogeneity in cluster randomized trials with linear mixed models
by: Baumann, Mary Ryan, et al.
Published: (2025)

Eliciting prior information from clinical trials via calibrated Bayes factor
by: Demartino, Roberto Macrì, et al.
Published: (2024)

Evaluating treatment effects on longitudinal outcomes with attrition due to death: Methods for a two-dimentional estimand with a case study in Quality of Life
by: Reynders, Dries, et al.
Published: (2025)

Priming bias versus post-treatment bias in experimental designs
by: Blackwell, Matthew, et al.
Published: (2023)

Causal language jumps in clinical practice guidelines for diabetes management
by: Wang, Keling, et al.
Published: (2025)

Grace periods in comparative effectiveness studies of sustained treatments
by: Wanis, Kerollos Nashat, et al.
Published: (2022)

Doubly protected estimation for survival outcomes utilizing external controls for randomized clinical trials
by: Gao, Chenyin, et al.
Published: (2024)

Multilevel functional distributional models with application to continuous glucose monitoring in diabetes clinical trials
by: Matabuena, Marcos, et al.
Published: (2024)

One-sample survival tests in the presence of non-proportional hazards in oncology clinical trials
by: Szurewsky, Chloé, et al.
Published: (2025)

Evaluating the impact of outcome delay on the efficiency of two-arm group-sequential trials
by: Mukherjee, Aritra, et al.
Published: (2023)

Evaluating virtual-control-augmented trials for reproducing treatment effect from original RCTs
by: Fernandes, Alex, et al.
Published: (2025)

A non-parametric U-statistic testing approach for multi-arm clinical trials with multivariate longitudinal data
by: Ghosh, Dhrubajyoti, et al.
Published: (2024)

A novel longitudinal rank-sum test for multiple primary endpoints in clinical trials: Applications to neurodegenerative disorders
by: Xu, Xiaoming, et al.
Published: (2024)

Comparison of Bayesian methods for extrapolation of treatment effects: a large scale simulation study
by: Fauvel, Tristan, et al.
Published: (2025)

Multiply robust estimation for causal survival analysis with treatment noncompliance
by: Cheng, Chao, et al.
Published: (2023)

Optimal designs for identifying effective doses in drug combination studies
by: Schürmeyer, Leonie, et al.
Published: (2025)

Multivariate incremental effects for continuous treatments: Studying the health effects of environmental mixtures
by: Huang, Zhuochao, et al.
Published: (2026)

Target trial emulation without matching: a more efficient approach for evaluating vaccine effectiveness using observational data
by: Wu, Emily, et al.
Published: (2025)

Simulation-based Bayesian predictive probability of success for interim monitoring of clinical trials with competing event data: two case studies
by: Micoli, Chiara, et al.
Published: (2024)

Methods for non-proportional hazards in clinical trials: A systematic review
by: Bardo, Maximilian, et al.
Published: (2023)

Estimating treatment duration effects via clone-censor-weight: a breast cancer case study
by: Voinot, Charlotte, et al.
Published: (2026)