Mismatch Negativity: time for deconstruction

Fuente: arXiv
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Hauptverfasser: Lecaignard, Francoise, Mattout, Jeremie
Format: Preprint
Veröffentlicht: 2023
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author Lecaignard, Francoise
Mattout, Jeremie
author_facet Lecaignard, Francoise
Mattout, Jeremie
contents Error signals are the cornerstone of predictive coding and are widely considered essential to sensory perception and beyond. The mismatch negativity (MMN) is arguably the most emblematic and most studied brain error signal. It is affected in many brain disorders. However, its precise algorithmic function and the underlying physiology remain mysterious. Over the past decade, theoretical and computational explanations have been put forward. They highlight a paradox: the MMN is considered a signature of context-dependent perceptual learning, although it is defined as an evoked response averaged across trials, thus neglecting the information carried by error signal fluctuations over time. We propose to deconstruct the MMN, by virtue of hypothesis driven computational approaches whose aim it to account for these fluctuations.
format Preprint
id arxiv_https___arxiv_org_abs_2310_11247
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Mismatch Negativity: time for deconstruction
Lecaignard, Francoise
Mattout, Jeremie
Neurons and Cognition
Error signals are the cornerstone of predictive coding and are widely considered essential to sensory perception and beyond. The mismatch negativity (MMN) is arguably the most emblematic and most studied brain error signal. It is affected in many brain disorders. However, its precise algorithmic function and the underlying physiology remain mysterious. Over the past decade, theoretical and computational explanations have been put forward. They highlight a paradox: the MMN is considered a signature of context-dependent perceptual learning, although it is defined as an evoked response averaged across trials, thus neglecting the information carried by error signal fluctuations over time. We propose to deconstruct the MMN, by virtue of hypothesis driven computational approaches whose aim it to account for these fluctuations.
title Mismatch Negativity: time for deconstruction
topic Neurons and Cognition
url https://arxiv.org/abs/2310.11247