Measuring arrangement and size distributions of flowing droplets in microchannels through deep learning

Fuente: arXiv
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Autori principali: Durve, Mihir, Orsini, Sibilla, Tiribocchi, Adriano, Montessori, Andrea, Tucny, Jean-Michel, Lauricella, Marco, Camposeo, Andrea, Pisignano, Dario, Succi, Sauro
Natura: Preprint
Pubblicazione: 2023
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author Durve, Mihir
Orsini, Sibilla
Tiribocchi, Adriano
Montessori, Andrea
Tucny, Jean-Michel
Lauricella, Marco
Camposeo, Andrea
Pisignano, Dario
Succi, Sauro
author_facet Durve, Mihir
Orsini, Sibilla
Tiribocchi, Adriano
Montessori, Andrea
Tucny, Jean-Michel
Lauricella, Marco
Camposeo, Andrea
Pisignano, Dario
Succi, Sauro
contents In microfluidic systems, droplets undergo intricate deformations as they traverse flow-focusing junctions, posing a challenging task for accurate measurement, especially during short transit times. This study investigates the physical behavior of droplets within dense emulsions in diverse microchannel geometries, specifically focusing on the impact of varying opening angles within the primary channel and injection rates of fluid components. Employing a sophisticated droplet tracking tool based on deep-learning techniques, we analyze multiple frames from flow-focusing experiments to quantitatively characterize droplet deformation in terms of ratio between maximum width and height and propensity to form liquid with hexagonal crystalline order. Our findings reveal the existence of an optimal opening angle where shape deformations are minimal and crystal-like arrangement is maximal. Variations of fluid injection rates are also found to affect size and packing fraction of the emulsion in the exit channel. This paper offers insights into deformations, size and structure of fluid emulsions relative to microchannel geometry and other flow-related parameters captured through machine learning, with potential implications for the design of microchips utilized in cellular transport and tissue engineering applications.
format Preprint
id arxiv_https___arxiv_org_abs_2310_19374
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Measuring arrangement and size distributions of flowing droplets in microchannels through deep learning
Durve, Mihir
Orsini, Sibilla
Tiribocchi, Adriano
Montessori, Andrea
Tucny, Jean-Michel
Lauricella, Marco
Camposeo, Andrea
Pisignano, Dario
Succi, Sauro
Fluid Dynamics
In microfluidic systems, droplets undergo intricate deformations as they traverse flow-focusing junctions, posing a challenging task for accurate measurement, especially during short transit times. This study investigates the physical behavior of droplets within dense emulsions in diverse microchannel geometries, specifically focusing on the impact of varying opening angles within the primary channel and injection rates of fluid components. Employing a sophisticated droplet tracking tool based on deep-learning techniques, we analyze multiple frames from flow-focusing experiments to quantitatively characterize droplet deformation in terms of ratio between maximum width and height and propensity to form liquid with hexagonal crystalline order. Our findings reveal the existence of an optimal opening angle where shape deformations are minimal and crystal-like arrangement is maximal. Variations of fluid injection rates are also found to affect size and packing fraction of the emulsion in the exit channel. This paper offers insights into deformations, size and structure of fluid emulsions relative to microchannel geometry and other flow-related parameters captured through machine learning, with potential implications for the design of microchips utilized in cellular transport and tissue engineering applications.
title Measuring arrangement and size distributions of flowing droplets in microchannels through deep learning
topic Fluid Dynamics
url https://arxiv.org/abs/2310.19374