An open-source, three-dimensional growth model of the mandible

Fuente: arXiv
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Hauptverfasser: Klop, Cornelis, Schreurs, Ruud, De Jong, Guido A, Klinkenberg, Edwin TM, Vespasiano, Valeria, Rood, Naomi L, Niehe, Valerie G, Soerdjbalie-Maikoe, Vidija, Van Goethem, Alexia, De Bakker, Bernadette S, Maal, Thomas JJ, Nolte, Jitske W, Becking, Alfred G
Format: Preprint
Veröffentlicht: 2023
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author Klop, Cornelis
Schreurs, Ruud
De Jong, Guido A
Klinkenberg, Edwin TM
Vespasiano, Valeria
Rood, Naomi L
Niehe, Valerie G
Soerdjbalie-Maikoe, Vidija
Van Goethem, Alexia
De Bakker, Bernadette S
Maal, Thomas JJ
Nolte, Jitske W
Becking, Alfred G
author_facet Klop, Cornelis
Schreurs, Ruud
De Jong, Guido A
Klinkenberg, Edwin TM
Vespasiano, Valeria
Rood, Naomi L
Niehe, Valerie G
Soerdjbalie-Maikoe, Vidija
Van Goethem, Alexia
De Bakker, Bernadette S
Maal, Thomas JJ
Nolte, Jitske W
Becking, Alfred G
contents The available reference data for the mandible and mandibular growth consists primarily of two-dimensional linear or angular measurements. The aim of this study was to create the first open-source, three-dimensional statistical shape model of the mandible that spans the complete growth period. Computed tomography scans of 678 mandibles from children and young adults between 0 and 22 years old were included in the model. The mandibles were segmented using a semi-automatic or automatic (artificial intelligence-based) segmentation method. Point correspondence among the samples was achieved by rigid registration, followed by non-rigid registration of a symmetrical template onto each sample. The registration process was validated with adequate results. Principal component analysis was used to gain insight in the variation within the dataset and to investigate age-related changes and sexual dimorphism. The presented growth model is accessible globally and free-of-charge for scientists, physicians and forensic investigators for any kind of purpose deemed suitable. The versatility of the model opens up new possibilities in the fields of oral and maxillofacial surgery, forensic sciences or biological anthropology. In clinical settings, the model may aid diagnostic decision-making, treatment planning and treatment evaluation.
format Preprint
id arxiv_https___arxiv_org_abs_2311_00392
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle An open-source, three-dimensional growth model of the mandible
Klop, Cornelis
Schreurs, Ruud
De Jong, Guido A
Klinkenberg, Edwin TM
Vespasiano, Valeria
Rood, Naomi L
Niehe, Valerie G
Soerdjbalie-Maikoe, Vidija
Van Goethem, Alexia
De Bakker, Bernadette S
Maal, Thomas JJ
Nolte, Jitske W
Becking, Alfred G
Tissues and Organs
The available reference data for the mandible and mandibular growth consists primarily of two-dimensional linear or angular measurements. The aim of this study was to create the first open-source, three-dimensional statistical shape model of the mandible that spans the complete growth period. Computed tomography scans of 678 mandibles from children and young adults between 0 and 22 years old were included in the model. The mandibles were segmented using a semi-automatic or automatic (artificial intelligence-based) segmentation method. Point correspondence among the samples was achieved by rigid registration, followed by non-rigid registration of a symmetrical template onto each sample. The registration process was validated with adequate results. Principal component analysis was used to gain insight in the variation within the dataset and to investigate age-related changes and sexual dimorphism. The presented growth model is accessible globally and free-of-charge for scientists, physicians and forensic investigators for any kind of purpose deemed suitable. The versatility of the model opens up new possibilities in the fields of oral and maxillofacial surgery, forensic sciences or biological anthropology. In clinical settings, the model may aid diagnostic decision-making, treatment planning and treatment evaluation.
title An open-source, three-dimensional growth model of the mandible
topic Tissues and Organs
url https://arxiv.org/abs/2311.00392