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Main Authors: Dalal, Sumit, Tilwani, Deepa, Roy, Kaushik, Gaur, Manas, Jain, Sarika, Shalin, Valerie, Sheth, Amit
Format: Preprint
Published: 2023
Subjects:
Online Access:https://arxiv.org/abs/2311.13852
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author Dalal, Sumit
Tilwani, Deepa
Roy, Kaushik
Gaur, Manas
Jain, Sarika
Shalin, Valerie
Sheth, Amit
author_facet Dalal, Sumit
Tilwani, Deepa
Roy, Kaushik
Gaur, Manas
Jain, Sarika
Shalin, Valerie
Sheth, Amit
contents The lack of explainability using relevant clinical knowledge hinders the adoption of Artificial Intelligence-powered analysis of unstructured clinical dialogue. A wealth of relevant, untapped Mental Health (MH) data is available in online communities, providing the opportunity to address the explainability problem with substantial potential impact as a screening tool for both online and offline applications. We develop a method to enhance attention in popular transformer models and generate clinician-understandable explanations for classification by incorporating external clinical knowledge. Inspired by how clinicians rely on their expertise when interacting with patients, we leverage relevant clinical knowledge to model patient inputs, providing meaningful explanations for classification. This will save manual review time and engender trust. We develop such a system in the context of MH using clinical practice guidelines (CPG) for diagnosing depression, a mental health disorder of global concern. We propose an application-specific language model called ProcesS knowledge-infused cross ATtention (PSAT), which incorporates CPGs when computing attention. Through rigorous evaluation on three expert-curated datasets related to depression, we demonstrate application-relevant explainability of PSAT. PSAT also surpasses the performance of nine baseline models and can provide explanations where other baselines fall short. We transform a CPG resource focused on depression, such as the Patient Health Questionnaire (e.g. PHQ-9) and related questions, into a machine-readable ontology using SNOMED-CT. With this resource, PSAT enhances the ability of models like GPT-3.5 to generate application-relevant explanations.
format Preprint
id arxiv_https___arxiv_org_abs_2311_13852
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle A Cross Attention Approach to Diagnostic Explainability using Clinical Practice Guidelines for Depression
Dalal, Sumit
Tilwani, Deepa
Roy, Kaushik
Gaur, Manas
Jain, Sarika
Shalin, Valerie
Sheth, Amit
Artificial Intelligence
The lack of explainability using relevant clinical knowledge hinders the adoption of Artificial Intelligence-powered analysis of unstructured clinical dialogue. A wealth of relevant, untapped Mental Health (MH) data is available in online communities, providing the opportunity to address the explainability problem with substantial potential impact as a screening tool for both online and offline applications. We develop a method to enhance attention in popular transformer models and generate clinician-understandable explanations for classification by incorporating external clinical knowledge. Inspired by how clinicians rely on their expertise when interacting with patients, we leverage relevant clinical knowledge to model patient inputs, providing meaningful explanations for classification. This will save manual review time and engender trust. We develop such a system in the context of MH using clinical practice guidelines (CPG) for diagnosing depression, a mental health disorder of global concern. We propose an application-specific language model called ProcesS knowledge-infused cross ATtention (PSAT), which incorporates CPGs when computing attention. Through rigorous evaluation on three expert-curated datasets related to depression, we demonstrate application-relevant explainability of PSAT. PSAT also surpasses the performance of nine baseline models and can provide explanations where other baselines fall short. We transform a CPG resource focused on depression, such as the Patient Health Questionnaire (e.g. PHQ-9) and related questions, into a machine-readable ontology using SNOMED-CT. With this resource, PSAT enhances the ability of models like GPT-3.5 to generate application-relevant explanations.
title A Cross Attention Approach to Diagnostic Explainability using Clinical Practice Guidelines for Depression
topic Artificial Intelligence
url https://arxiv.org/abs/2311.13852