Assumption-Lean and Data-Adaptive Post-Prediction Inference

Fuente: arXiv
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Auteurs principaux: Miao, Jiacheng, Miao, Xinran, Wu, Yixuan, Zhao, Jiwei, Lu, Qiongshi
Format: Preprint
Publié: 2023
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author Miao, Jiacheng
Miao, Xinran
Wu, Yixuan
Zhao, Jiwei
Lu, Qiongshi
author_facet Miao, Jiacheng
Miao, Xinran
Wu, Yixuan
Zhao, Jiwei
Lu, Qiongshi
contents A primary challenge facing modern scientific research is the limited availability of gold-standard data which can be costly, labor-intensive, or invasive to obtain. With the rapid development of machine learning (ML), scientists can now employ ML algorithms to predict gold-standard outcomes with variables that are easier to obtain. However, these predicted outcomes are often used directly in subsequent statistical analyses, ignoring imprecision and heterogeneity introduced by the prediction procedure. This will likely result in false positive findings and invalid scientific conclusions. In this work, we introduce PoSt-Prediction Adaptive inference (PSPA) that allows valid and powerful inference based on ML-predicted data. Its "assumption-lean" property guarantees reliable statistical inference without assumptions on the ML prediction. Its "data-adaptive" feature guarantees an efficiency gain over existing methods, regardless of the accuracy of ML prediction. We demonstrate the statistical superiority and broad applicability of our method through simulations and real-data applications.
format Preprint
id arxiv_https___arxiv_org_abs_2311_14220
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Assumption-Lean and Data-Adaptive Post-Prediction Inference
Miao, Jiacheng
Miao, Xinran
Wu, Yixuan
Zhao, Jiwei
Lu, Qiongshi
Methodology
Machine Learning
A primary challenge facing modern scientific research is the limited availability of gold-standard data which can be costly, labor-intensive, or invasive to obtain. With the rapid development of machine learning (ML), scientists can now employ ML algorithms to predict gold-standard outcomes with variables that are easier to obtain. However, these predicted outcomes are often used directly in subsequent statistical analyses, ignoring imprecision and heterogeneity introduced by the prediction procedure. This will likely result in false positive findings and invalid scientific conclusions. In this work, we introduce PoSt-Prediction Adaptive inference (PSPA) that allows valid and powerful inference based on ML-predicted data. Its "assumption-lean" property guarantees reliable statistical inference without assumptions on the ML prediction. Its "data-adaptive" feature guarantees an efficiency gain over existing methods, regardless of the accuracy of ML prediction. We demonstrate the statistical superiority and broad applicability of our method through simulations and real-data applications.
title Assumption-Lean and Data-Adaptive Post-Prediction Inference
topic Methodology
Machine Learning
url https://arxiv.org/abs/2311.14220