Automatic Report Generation for Histopathology images using pre-trained Vision Transformers and BERT

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Hauptverfasser: Sengupta, Saurav, Brown, Donald E.
Format: Preprint
Veröffentlicht: 2023
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author Sengupta, Saurav
Brown, Donald E.
author_facet Sengupta, Saurav
Brown, Donald E.
contents Deep learning for histopathology has been successfully used for disease classification, image segmentation and more. However, combining image and text modalities using current state-of-the-art (SOTA) methods has been a challenge due to the high resolution of histopathology images. Automatic report generation for histopathology images is one such challenge. In this work, we show that using an existing pre-trained Vision Transformer (ViT) to encode 4096x4096 sized patches of the Whole Slide Image (WSI) and a pre-trained Bidirectional Encoder Representations from Transformers (BERT) model for language modeling-based decoder for report generation, we can build a performant and portable report generation mechanism that takes into account the whole high resolution image. Our method allows us to not only generate and evaluate captions that describe the image, but also helps us classify the image into tissue types and the gender of the patient as well. Our best performing model achieves a 89.52% accuracy in Tissue Type classification with a BLEU-4 score of 0.12 in our caption generation task.
format Preprint
id arxiv_https___arxiv_org_abs_2312_01435
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Automatic Report Generation for Histopathology images using pre-trained Vision Transformers and BERT
Sengupta, Saurav
Brown, Donald E.
Computer Vision and Pattern Recognition
Deep learning for histopathology has been successfully used for disease classification, image segmentation and more. However, combining image and text modalities using current state-of-the-art (SOTA) methods has been a challenge due to the high resolution of histopathology images. Automatic report generation for histopathology images is one such challenge. In this work, we show that using an existing pre-trained Vision Transformer (ViT) to encode 4096x4096 sized patches of the Whole Slide Image (WSI) and a pre-trained Bidirectional Encoder Representations from Transformers (BERT) model for language modeling-based decoder for report generation, we can build a performant and portable report generation mechanism that takes into account the whole high resolution image. Our method allows us to not only generate and evaluate captions that describe the image, but also helps us classify the image into tissue types and the gender of the patient as well. Our best performing model achieves a 89.52% accuracy in Tissue Type classification with a BLEU-4 score of 0.12 in our caption generation task.
title Automatic Report Generation for Histopathology images using pre-trained Vision Transformers and BERT
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2312.01435