The Gaussian-Linear Hidden Markov model: a Python package

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Hauptverfasser: Vidaurre, Diego, Masaracchia, Laura, Larsen, Nick Y., Ruijters, Lenno R. P. T, Alonso, Sonsoles, Ahrends, Christine, Woolrich, Mark W.
Format: Preprint
Veröffentlicht: 2023
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author Vidaurre, Diego
Masaracchia, Laura
Larsen, Nick Y.
Ruijters, Lenno R. P. T
Alonso, Sonsoles
Ahrends, Christine
Woolrich, Mark W.
author_facet Vidaurre, Diego
Masaracchia, Laura
Larsen, Nick Y.
Ruijters, Lenno R. P. T
Alonso, Sonsoles
Ahrends, Christine
Woolrich, Mark W.
contents We propose the Gaussian-Linear Hidden Markov model (GLHMM), a generalisation of different types of HMMs commonly used in neuroscience. In short, the GLHMM is a general framework where linear regression is used to flexibly parameterise the Gaussian state distribution, thereby accommodating a wide range of uses -- including unsupervised, encoding and decoding models. GLHMM is implemented as a Python toolbox with an emphasis on statistical testing and out-of-sample prediction -- i.e. aimed at finding and characterising brain-behaviour associations. The toolbox uses a stochastic variational inference approach, enabling it to handle large data sets at reasonable computational time. The approach can be applied to several data modalities, including animal recordings or non-brain data, and applied over a broad range of experimental paradigms. For demonstration, we show examples with fMRI, electrocorticography, magnetoencephalography and pupillometry.
format Preprint
id arxiv_https___arxiv_org_abs_2312_07151
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle The Gaussian-Linear Hidden Markov model: a Python package
Vidaurre, Diego
Masaracchia, Laura
Larsen, Nick Y.
Ruijters, Lenno R. P. T
Alonso, Sonsoles
Ahrends, Christine
Woolrich, Mark W.
Neurons and Cognition
Machine Learning
We propose the Gaussian-Linear Hidden Markov model (GLHMM), a generalisation of different types of HMMs commonly used in neuroscience. In short, the GLHMM is a general framework where linear regression is used to flexibly parameterise the Gaussian state distribution, thereby accommodating a wide range of uses -- including unsupervised, encoding and decoding models. GLHMM is implemented as a Python toolbox with an emphasis on statistical testing and out-of-sample prediction -- i.e. aimed at finding and characterising brain-behaviour associations. The toolbox uses a stochastic variational inference approach, enabling it to handle large data sets at reasonable computational time. The approach can be applied to several data modalities, including animal recordings or non-brain data, and applied over a broad range of experimental paradigms. For demonstration, we show examples with fMRI, electrocorticography, magnetoencephalography and pupillometry.
title The Gaussian-Linear Hidden Markov model: a Python package
topic Neurons and Cognition
Machine Learning
url https://arxiv.org/abs/2312.07151