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| Autori principali: | , , , , , , , , |
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| Natura: | Preprint |
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2023
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| Accesso online: | https://arxiv.org/abs/2312.11426 |
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| _version_ | 1866917696316112896 |
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| author | Trivedi, Zubin Wychowaniec, Jacek K. Gehweiler, Dominic Sprecher, Christoph M. Boger, Andreas Gueorguiev, Boyko D'Este, Matteo Ricken, Tim Röhrle, Oliver |
| author_facet | Trivedi, Zubin Wychowaniec, Jacek K. Gehweiler, Dominic Sprecher, Christoph M. Boger, Andreas Gueorguiev, Boyko D'Este, Matteo Ricken, Tim Röhrle, Oliver |
| contents | Vertebroplasty is a minimally invasive surgical procedure used to treat vertebral fractures, which conventionally involves injecting polymethylmethacrylate (PMMA) bone cement into the fractured vertebra. A common risk associated with vertebroplasty is cement leaking out of the vertebra during the injection, which may occur due to a lack of understanding of the bone cement's complex flow behavior. Therefore, experiments to quantify the cement's flow properties are necessary for understanding and proper handling of the bone cement. In this study, we aimed to characterize the behavior of the PMMA bone cement in its curing stages to obtain parameters that govern the flow behavior during the injection. We used rotational and oscillatory rheometry for our measurements, as well as a custom-made injector setup that replicated a typical vertebroplasty setting. Our results showed that the complex viscoelastic behavior of the bone cement is significantly affected by deformations and temperature. We found that the results from rotational tests, often used for characterizing the bone cement, are susceptible to measurement artifacts caused by wall slip and "ridge"-like formations in the test sample. We also found the Cox-Merz rule to be conditionally valid, which affects the use of oscillatory tests to obtain shear-thinning characteristics for the bone cement. Our findings identify important differences in the measured flow behavior of PMMA bone cement when assessed by different rheological methods, understanding which is crucial for its risk-free usage in downstream medical applications. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2312_11426 |
| institution | arXiv |
| publishDate | 2023 |
| record_format | arxiv |
| spellingShingle | Rheological Analysis and Evaluation of Measurement Techniques for the Curing Polymethylmethacrylate Bone Cement in Vertebroplasty Trivedi, Zubin Wychowaniec, Jacek K. Gehweiler, Dominic Sprecher, Christoph M. Boger, Andreas Gueorguiev, Boyko D'Este, Matteo Ricken, Tim Röhrle, Oliver Soft Condensed Matter Fluid Dynamics Vertebroplasty is a minimally invasive surgical procedure used to treat vertebral fractures, which conventionally involves injecting polymethylmethacrylate (PMMA) bone cement into the fractured vertebra. A common risk associated with vertebroplasty is cement leaking out of the vertebra during the injection, which may occur due to a lack of understanding of the bone cement's complex flow behavior. Therefore, experiments to quantify the cement's flow properties are necessary for understanding and proper handling of the bone cement. In this study, we aimed to characterize the behavior of the PMMA bone cement in its curing stages to obtain parameters that govern the flow behavior during the injection. We used rotational and oscillatory rheometry for our measurements, as well as a custom-made injector setup that replicated a typical vertebroplasty setting. Our results showed that the complex viscoelastic behavior of the bone cement is significantly affected by deformations and temperature. We found that the results from rotational tests, often used for characterizing the bone cement, are susceptible to measurement artifacts caused by wall slip and "ridge"-like formations in the test sample. We also found the Cox-Merz rule to be conditionally valid, which affects the use of oscillatory tests to obtain shear-thinning characteristics for the bone cement. Our findings identify important differences in the measured flow behavior of PMMA bone cement when assessed by different rheological methods, understanding which is crucial for its risk-free usage in downstream medical applications. |
| title | Rheological Analysis and Evaluation of Measurement Techniques for the Curing Polymethylmethacrylate Bone Cement in Vertebroplasty |
| topic | Soft Condensed Matter Fluid Dynamics |
| url | https://arxiv.org/abs/2312.11426 |