Precise FWER Control for Gaussian Related Fields: Riding the SuRF to continuous land -- Part 1

Fuente: arXiv
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Autori principali: Telschow, Fabian JE, Davenport, Samuel
Natura: Preprint
Pubblicazione: 2023
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author Telschow, Fabian JE
Davenport, Samuel
author_facet Telschow, Fabian JE
Davenport, Samuel
contents The Gaussian Kinematic Formula (GKF) is a powerful and computationally efficient tool to perform statistical inference on random fields and became a well-established tool in the analysis of neuroimaging data. Using realistic error models, recent articles show that GKF based methods for \emph{voxelwise inference} lead to conservative control of the familywise error rate (FWER) and for cluster-size inference lead to inflated false positive rates. In this series of articles we identify and resolve the main causes of these shortcomings in the traditional usage of the GKF for voxelwise inference. This first part removes the \textit{good lattice assumption} and allows the data to be non-stationary, yet still assumes the data to be Gaussian. The latter assumption is resolved in part 2, where we also demonstrate that our GKF based methodology is non-conservative under realistic error models.
format Preprint
id arxiv_https___arxiv_org_abs_2312_13450
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Precise FWER Control for Gaussian Related Fields: Riding the SuRF to continuous land -- Part 1
Telschow, Fabian JE
Davenport, Samuel
Methodology
The Gaussian Kinematic Formula (GKF) is a powerful and computationally efficient tool to perform statistical inference on random fields and became a well-established tool in the analysis of neuroimaging data. Using realistic error models, recent articles show that GKF based methods for \emph{voxelwise inference} lead to conservative control of the familywise error rate (FWER) and for cluster-size inference lead to inflated false positive rates. In this series of articles we identify and resolve the main causes of these shortcomings in the traditional usage of the GKF for voxelwise inference. This first part removes the \textit{good lattice assumption} and allows the data to be non-stationary, yet still assumes the data to be Gaussian. The latter assumption is resolved in part 2, where we also demonstrate that our GKF based methodology is non-conservative under realistic error models.
title Precise FWER Control for Gaussian Related Fields: Riding the SuRF to continuous land -- Part 1
topic Methodology
url https://arxiv.org/abs/2312.13450