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| Main Authors: | , |
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| Format: | Preprint |
| Published: |
2023
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| Subjects: | |
| Online Access: | https://arxiv.org/abs/2312.16745 |
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| _version_ | 1866912342057418752 |
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| author | Donya, H. Umer, M. |
| author_facet | Donya, H. Umer, M. |
| contents | Boron neutron capture therapy is about a century old, but still current and active. In this treatment, a high absorption cross-section of boron is used for thermal neutrons and the excited state is decomposed into alpha and lithium ions. These daughter particles have a high LET value and transfer their energy to the surrounding cells. In this work, the neutron generator DD-110 is the neutron source of the treatment mode. Since the neutron generator produces fast neutrons, these must be thermalized to the energy range of the epithermal neutrons. The beam shaping assembly is used for this purpose. The effectiveness of the system is analyzed using in-air and in-phantom parameters. The system provides an acceptable ratio of thermal to epithermal flux, gamma dose to epithermal flux and beam collimation. However, the epithermal flux and the ratio of fast neutron dose to epithermal flux need to be further improved. This can be achieved by improving the performance of the neutron generator to 2E13 n/sec. The entire system is modeled and simulated with the MCNPX code. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2312_16745 |
| institution | arXiv |
| publishDate | 2023 |
| record_format | arxiv |
| spellingShingle | Optimization of dd110 neutron generator output for boron neutron capture therapy Donya, H. Umer, M. Accelerator Physics Medical Physics 00A79 F.2.2 Boron neutron capture therapy is about a century old, but still current and active. In this treatment, a high absorption cross-section of boron is used for thermal neutrons and the excited state is decomposed into alpha and lithium ions. These daughter particles have a high LET value and transfer their energy to the surrounding cells. In this work, the neutron generator DD-110 is the neutron source of the treatment mode. Since the neutron generator produces fast neutrons, these must be thermalized to the energy range of the epithermal neutrons. The beam shaping assembly is used for this purpose. The effectiveness of the system is analyzed using in-air and in-phantom parameters. The system provides an acceptable ratio of thermal to epithermal flux, gamma dose to epithermal flux and beam collimation. However, the epithermal flux and the ratio of fast neutron dose to epithermal flux need to be further improved. This can be achieved by improving the performance of the neutron generator to 2E13 n/sec. The entire system is modeled and simulated with the MCNPX code. |
| title | Optimization of dd110 neutron generator output for boron neutron capture therapy |
| topic | Accelerator Physics Medical Physics 00A79 F.2.2 |
| url | https://arxiv.org/abs/2312.16745 |