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Main Authors: Manjunatha, Kiran, Ranno, Anna, Shi, Jianye, Schaaps, Nicole, Nilcham, Pakhwan, Cornelissen, Anne, Vogt, Felix, Behr, Marek, Reese, Stefanie
Format: Preprint
Published: 2024
Subjects:
Online Access:https://arxiv.org/abs/2401.03961
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author Manjunatha, Kiran
Ranno, Anna
Shi, Jianye
Schaaps, Nicole
Nilcham, Pakhwan
Cornelissen, Anne
Vogt, Felix
Behr, Marek
Reese, Stefanie
author_facet Manjunatha, Kiran
Ranno, Anna
Shi, Jianye
Schaaps, Nicole
Nilcham, Pakhwan
Cornelissen, Anne
Vogt, Felix
Behr, Marek
Reese, Stefanie
contents The occurrence of in-stent restenosis following percutaneous coronary intervention highlights the need for the creation of computational tools that can extract pathophysiological insights and optimize interventional procedures on a patient-specific basis. In light of this, a comprehensive framework encompassing multiple physical phenomena is introduced in this work. This framework effectively captures the intricate interplay of chemical, mechanical, and biological factors. In addition, computational approaches for the extraction of hemodynamic indicators that modulate the severity of the restenotic process are devised. Thus, this marks a significant stride towards facilitating computer-assisted clinical methodologies.
format Preprint
id arxiv_https___arxiv_org_abs_2401_03961
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle In silico reproduction of the pathophysiology of in-stent restenosis
Manjunatha, Kiran
Ranno, Anna
Shi, Jianye
Schaaps, Nicole
Nilcham, Pakhwan
Cornelissen, Anne
Vogt, Felix
Behr, Marek
Reese, Stefanie
Biological Physics
Fluid Dynamics
The occurrence of in-stent restenosis following percutaneous coronary intervention highlights the need for the creation of computational tools that can extract pathophysiological insights and optimize interventional procedures on a patient-specific basis. In light of this, a comprehensive framework encompassing multiple physical phenomena is introduced in this work. This framework effectively captures the intricate interplay of chemical, mechanical, and biological factors. In addition, computational approaches for the extraction of hemodynamic indicators that modulate the severity of the restenotic process are devised. Thus, this marks a significant stride towards facilitating computer-assisted clinical methodologies.
title In silico reproduction of the pathophysiology of in-stent restenosis
topic Biological Physics
Fluid Dynamics
url https://arxiv.org/abs/2401.03961