Quasi-equilibrium states and phase transitions in biological evolution

Fuente: arXiv
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Autori principali: Romanenko, Artem, Vanchurin, Vitaly
Natura: Preprint
Pubblicazione: 2024
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author Romanenko, Artem
Vanchurin, Vitaly
author_facet Romanenko, Artem
Vanchurin, Vitaly
contents We develop a macroscopic description of the evolutionary dynamics by following the temporal dynamics of the total Shannon entropy of sequences, denoted by $S$, and the average Hamming distance between them, denoted by $H$. We argue that a biological system can persist in the so-called quasi-equilibrium state for an extended period, characterized by strong correlations between $S$ and $H$, before undergoing a phase transition to another quasi-equilibrium state. To demonstrate the results, we conducted a statistical analysis of SARS-CoV-2 data from the United Kingdom during the period between March, 2020 and December, 2023. From a purely theoretical perspective, this allows us to systematically study various types of phase transitions described by a discontinuous change in the thermodynamic parameters. From a more practical point of view, the analysis can be used, for example, as an early warning system for pandemics.
format Preprint
id arxiv_https___arxiv_org_abs_2401_04444
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Quasi-equilibrium states and phase transitions in biological evolution
Romanenko, Artem
Vanchurin, Vitaly
Populations and Evolution
We develop a macroscopic description of the evolutionary dynamics by following the temporal dynamics of the total Shannon entropy of sequences, denoted by $S$, and the average Hamming distance between them, denoted by $H$. We argue that a biological system can persist in the so-called quasi-equilibrium state for an extended period, characterized by strong correlations between $S$ and $H$, before undergoing a phase transition to another quasi-equilibrium state. To demonstrate the results, we conducted a statistical analysis of SARS-CoV-2 data from the United Kingdom during the period between March, 2020 and December, 2023. From a purely theoretical perspective, this allows us to systematically study various types of phase transitions described by a discontinuous change in the thermodynamic parameters. From a more practical point of view, the analysis can be used, for example, as an early warning system for pandemics.
title Quasi-equilibrium states and phase transitions in biological evolution
topic Populations and Evolution
url https://arxiv.org/abs/2401.04444