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Autores principales: Tobin, Joshua, Black, Michaela, Ng, James, Rankin, Debbie, Wallace, Jonathan, Hughes, Catherine, Hoey, Leane, Moore, Adrian, Wang, Jinling, Horigan, Geraldine, Carlin, Paul, McNulty, Helene, Molloy, Anne M, Zhang, Mimi
Formato: Preprint
Publicado: 2024
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Acceso en línea:https://arxiv.org/abs/2401.04693
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author Tobin, Joshua
Black, Michaela
Ng, James
Rankin, Debbie
Wallace, Jonathan
Hughes, Catherine
Hoey, Leane
Moore, Adrian
Wang, Jinling
Horigan, Geraldine
Carlin, Paul
McNulty, Helene
Molloy, Anne M
Zhang, Mimi
author_facet Tobin, Joshua
Black, Michaela
Ng, James
Rankin, Debbie
Wallace, Jonathan
Hughes, Catherine
Hoey, Leane
Moore, Adrian
Wang, Jinling
Horigan, Geraldine
Carlin, Paul
McNulty, Helene
Molloy, Anne M
Zhang, Mimi
contents The Latent Block Model (LBM) is a prominent model-based co-clustering method, returning parametric representations of each block cluster and allowing the use of well-grounded model selection methods. The LBM, while adapted in literature to handle different feature types, cannot be applied to datasets consisting of multiple disjoint sets of features, termed views, for a common set of observations. In this work, we introduce the multi-view LBM, extending the LBM method to multi-view data, where each view marginally follows an LBM. In the case of two views, the dependence between them is captured by a cluster membership matrix, and we aim to learn the structure of this matrix. We develop a likelihood-based approach in which parameter estimation uses a stochastic EM algorithm integrating a Gibbs sampler, and an ICL criterion is derived to determine the number of row and column clusters in each view. To motivate the application of multi-view methods, we extend recent work developing hypothesis tests for the null hypothesis that clusters of observations in each view are independent of each other. The testing procedure is integrated into the model estimation strategy. Furthermore, we introduce a penalty scheme to generate sparse row clusterings. We verify the performance of the developed algorithm using synthetic datasets, and provide guidance for optimal parameter selection. Finally, the multi-view co-clustering method is applied to a complex genomics dataset, and is shown to provide new insights for high-dimension multi-view problems.
format Preprint
id arxiv_https___arxiv_org_abs_2401_04693
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Co-Clustering Multi-View Data Using the Latent Block Model
Tobin, Joshua
Black, Michaela
Ng, James
Rankin, Debbie
Wallace, Jonathan
Hughes, Catherine
Hoey, Leane
Moore, Adrian
Wang, Jinling
Horigan, Geraldine
Carlin, Paul
McNulty, Helene
Molloy, Anne M
Zhang, Mimi
Methodology
The Latent Block Model (LBM) is a prominent model-based co-clustering method, returning parametric representations of each block cluster and allowing the use of well-grounded model selection methods. The LBM, while adapted in literature to handle different feature types, cannot be applied to datasets consisting of multiple disjoint sets of features, termed views, for a common set of observations. In this work, we introduce the multi-view LBM, extending the LBM method to multi-view data, where each view marginally follows an LBM. In the case of two views, the dependence between them is captured by a cluster membership matrix, and we aim to learn the structure of this matrix. We develop a likelihood-based approach in which parameter estimation uses a stochastic EM algorithm integrating a Gibbs sampler, and an ICL criterion is derived to determine the number of row and column clusters in each view. To motivate the application of multi-view methods, we extend recent work developing hypothesis tests for the null hypothesis that clusters of observations in each view are independent of each other. The testing procedure is integrated into the model estimation strategy. Furthermore, we introduce a penalty scheme to generate sparse row clusterings. We verify the performance of the developed algorithm using synthetic datasets, and provide guidance for optimal parameter selection. Finally, the multi-view co-clustering method is applied to a complex genomics dataset, and is shown to provide new insights for high-dimension multi-view problems.
title Co-Clustering Multi-View Data Using the Latent Block Model
topic Methodology
url https://arxiv.org/abs/2401.04693