Cover Image

Prediction of causal genes at GWAS loci with pleiotropic gene regulatory effects using sets of correlated instrumental variables

Fuente: arXiv

Saved in:

Bibliographic Details
Main Authors:	Khan, Mariyam, Ludl, Adriaan-Alexander, Bankier, Sean, Bjorkegren, Johan, Michoel, Tom
Format:	Preprint
Published:	2024
Subjects:	Methodology Quantitative Methods
Online Access:	Acceder al recurso
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

A network-driven framework for enhancing gene-disease association studies in coronary artery disease
by: Mohammad, Gutama Ibrahim, et al.
Published: (2025)

Predicting the genetic component of gene expression using gene regulatory networks
by: Mohammad, Gutama Ibrahim, et al.
Published: (2024)

Association of normalization, non-differentially expressed genes and data source with machine learning performance in intra-dataset or cross-dataset modelling of transcriptomic and clinical data
by: Deng, Fei, et al.
Published: (2025)

Negative Spillover: A Potential Source of Bias in Pragmatic Clinical Trials
by: Mann, Sean
Published: (2023)

Normalization and selecting non-differentially expressed genes improve machine learning modelling of cross-platform transcriptomic data
by: Deng, Fei, et al.
Published: (2025)

Causal inference in drug discovery and development
by: Michoel, Tom, et al.
Published: (2022)

Assessing Time Series Correlation Significance: A Parametric Approach with Application to Physiological Signals
by: Medrano, Johan, et al.
Published: (2024)

Deciphering interventional dynamical causality from non-intervention complex systems
by: Shi, Jifan, et al.
Published: (2024)

Multiblock variable influence on orthogonal projections (MB-VIOP) for enhanced interpretation of total, global, local and unique variations in OnPLS models
by: Galindo-Prieto, B., et al.
Published: (2020)

A nonparametric approach to practical identifiability of nonlinear mixed effects models
by: Cassidy, Tyler, et al.
Published: (2025)

A computational framework for optimal and Model Predictive Control of stochastic gene regulatory networks
by: Faquir, Hamza, et al.
Published: (2024)

Improving Genomic Prediction using High-dimensional Secondary Phenotypes: the Genetic Latent Factor Approach
by: Melsen, Killian A. C., et al.
Published: (2024)

Model-based calibration of gear-specific fish abundance survey data as a change-of-support problem
by: Chiu, Grace S., et al.
Published: (2025)

Amortized Phylodynamic Inference with Neural Bayes Estimators and Recursive Neural Networks
by: Zarebski, Alexander E., et al.
Published: (2026)

Multilevel testing of constraints induced by structural equation modeling in fMRI effective connectivity analysis: A proof of concept
by: Marrelec, G., et al.
Published: (2024)

Bayesian variable selection in a Cox proportional hazards model with the "Sum of Single Effects" prior
by: Yang, Yunqi, et al.
Published: (2025)

A likelihood-based Bayesian inference framework for the calibration of and selection between stochastic velocity-jump models
by: Ceccarelli, Arianna, et al.
Published: (2025)

Intrinsic limits of timekeeping precision in gene regulatory cascades
by: Hernandez, Juan Sebastian, et al.
Published: (2025)

Double trouble: Predicting new variant counts across two heterogeneous populations
by: Shen, Yunyi, et al.
Published: (2024)

A conceptual synthesis of causal assumptions for causal discovery and inference
by: Correia, Hannah E.
Published: (2025)

Nonparametric identification and efficient estimation of causal effects with instrumental variables
by: Levis, Alexander W., et al.
Published: (2024)

Informational blueprints reveal condition-dependent gene regulatory architectures
by: Gökmen, Doruk Efe, et al.
Published: (2026)

Data-Driven Switchback Experiments: Theoretical Tradeoffs and Empirical Bayes Designs
by: Xiong, Ruoxuan, et al.
Published: (2024)

Conformal Prediction Under Feedback Covariate Shift for Biomolecular Design
by: Fannjiang, Clara, et al.
Published: (2022)

An ADMM approach for multi-response regression with overlapping groups and interaction effects
by: Asenso, Theophilus Quachie, et al.
Published: (2023)

Realizing Common Random Numbers: Event-Keyed Hashing for Causally Valid Stochastic Models
by: Buffalo, Vince, et al.
Published: (2026)

ICBM community cancer registry analysis: a focus on Non-Hodgkin Lymphoma cases in missileers
by: Sanderson, Dawn L., et al.
Published: (2025)

Consistent diffusion matrix estimation from population time series
by: Forrow, Aden
Published: (2024)

Using Instruments for Selection to Adjust for Selection Bias in Mendelian Randomization
by: Gkatzionis, Apostolos, et al.
Published: (2022)

Lagged coherence: explicit and testable definition
by: Pascual-Marqui, Roberto D., et al.
Published: (2023)

Discriminating BCC Subtypes Using Entropy and Mutual Information from Dermoscopic Features
by: Matas, Iván, et al.
Published: (2025)

Beyond P-Values: Importing Quantitative Finance's Risk and Regret Metrics for AI in Learning Health Systems
by: Chakraborty, Richik
Published: (2026)

Semiparametric estimation of GLMs with interval-censored covariates via an augmented Turnbull estimator
by: Toloba, Andrea, et al.
Published: (2026)

Probabilities of causation and post-infection outcomes
by: Gonçalves, Bronner P.
Published: (2025)

OSSMM: An Open-Source Sleep Monitor and Modulator
by: Giordano, Jonny, et al.
Published: (2026)

Phenology curve estimation via a mixed model representation of functional principal components: Characterizing time series of satellite-derived vegetation indices
by: Tecuapetla-Gómez, Inder, et al.
Published: (2024)

Diagnosing overdispersion in longitudinal analyses with grouped nominal polytomous data
by: Salvador, Maria Letícia, et al.
Published: (2024)

Modelling longitudinal polytomous animal data using Bayesian hierarchical models
by: Salvador, Maria Letícia, et al.
Published: (2025)

Multimorbidity as a multistage disease process
by: Webster, Anthony J.
Published: (2025)

A decision-theoretic framework for uncertainty quantification in epidemiological modelling
by: Steyn, Nicholas, et al.
Published: (2025)