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| Main Authors: | , , , , , |
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| Format: | Preprint |
| Published: |
2024
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| Subjects: | |
| Online Access: | https://arxiv.org/abs/2401.06906 |
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Table of Contents:
- Traditional optical tweezers techniques often rely on high-power continuous wave (CW) lasers, which can introduce unwanted thermal effects and photodamage to delicate samples. To overcome these limitations, we demonstrate femtosecond laser assisted selective holding with ultra-low power (FLASH-UP). We find that the FLASH-UP exhibits a five times greater trap stiffness than CW-OT, and can trap at lower intensities. Furthermore, we demonstrate OT of different pathogenic bacteria species and find that FLASH-UP does not impact cell motility. These results pave the way for applications in sorting, bio-sensing, in vivo cell manipulation and single cell analysis.