MICA: Towards Explainable Skin Lesion Diagnosis via Multi-Level Image-Concept Alignment

Fuente: arXiv
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Autores principales: Bie, Yequan, Luo, Luyang, Chen, Hao
Formato: Preprint
Publicado: 2024
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author Bie, Yequan
Luo, Luyang
Chen, Hao
author_facet Bie, Yequan
Luo, Luyang
Chen, Hao
contents Black-box deep learning approaches have showcased significant potential in the realm of medical image analysis. However, the stringent trustworthiness requirements intrinsic to the medical field have catalyzed research into the utilization of Explainable Artificial Intelligence (XAI), with a particular focus on concept-based methods. Existing concept-based methods predominantly apply concept annotations from a single perspective (e.g., global level), neglecting the nuanced semantic relationships between sub-regions and concepts embedded within medical images. This leads to underutilization of the valuable medical information and may cause models to fall short in harmoniously balancing interpretability and performance when employing inherently interpretable architectures such as Concept Bottlenecks. To mitigate these shortcomings, we propose a multi-modal explainable disease diagnosis framework that meticulously aligns medical images and clinical-related concepts semantically at multiple strata, encompassing the image level, token level, and concept level. Moreover, our method allows for model intervention and offers both textual and visual explanations in terms of human-interpretable concepts. Experimental results on three skin image datasets demonstrate that our method, while preserving model interpretability, attains high performance and label efficiency for concept detection and disease diagnosis.
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id arxiv_https___arxiv_org_abs_2401_08527
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle MICA: Towards Explainable Skin Lesion Diagnosis via Multi-Level Image-Concept Alignment
Bie, Yequan
Luo, Luyang
Chen, Hao
Computer Vision and Pattern Recognition
Artificial Intelligence
Black-box deep learning approaches have showcased significant potential in the realm of medical image analysis. However, the stringent trustworthiness requirements intrinsic to the medical field have catalyzed research into the utilization of Explainable Artificial Intelligence (XAI), with a particular focus on concept-based methods. Existing concept-based methods predominantly apply concept annotations from a single perspective (e.g., global level), neglecting the nuanced semantic relationships between sub-regions and concepts embedded within medical images. This leads to underutilization of the valuable medical information and may cause models to fall short in harmoniously balancing interpretability and performance when employing inherently interpretable architectures such as Concept Bottlenecks. To mitigate these shortcomings, we propose a multi-modal explainable disease diagnosis framework that meticulously aligns medical images and clinical-related concepts semantically at multiple strata, encompassing the image level, token level, and concept level. Moreover, our method allows for model intervention and offers both textual and visual explanations in terms of human-interpretable concepts. Experimental results on three skin image datasets demonstrate that our method, while preserving model interpretability, attains high performance and label efficiency for concept detection and disease diagnosis.
title MICA: Towards Explainable Skin Lesion Diagnosis via Multi-Level Image-Concept Alignment
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2401.08527