Numerical Approximations and Convergence Analysis of Piecewise Diffusion Markov Processes, with Application to Glioma Cell Migration

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Hauptverfasser: Buckwar, Evelyn, Meddah, Amira
Format: Preprint
Veröffentlicht: 2024
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author Buckwar, Evelyn
Meddah, Amira
author_facet Buckwar, Evelyn
Meddah, Amira
contents In this paper, we focus on numerical approximations of Piecewise Diffusion Markov Processes (PDifMPs), particularly when the explicit flow maps are unavailable. Our approach is based on the thinning method for modelling the jump mechanism and combines the Euler-Maruyama scheme to approximate the underlying flow dynamics. For the proposed approximation schemes, we study both the mean-square and weak convergence. Weak convergence of the algorithms is established by a martingale problem formulation. Moreover, we employ these results to simulate the migration patterns exhibited by moving glioma cells at the microscopic level. Further, we develop and implement a splitting method for this PDifMP model and employ both the Thinned Euler-Maruyama and the splitting scheme in our simulation example, allowing us to compare both methods.
format Preprint
id arxiv_https___arxiv_org_abs_2401_13428
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Numerical Approximations and Convergence Analysis of Piecewise Diffusion Markov Processes, with Application to Glioma Cell Migration
Buckwar, Evelyn
Meddah, Amira
Numerical Analysis
Probability
In this paper, we focus on numerical approximations of Piecewise Diffusion Markov Processes (PDifMPs), particularly when the explicit flow maps are unavailable. Our approach is based on the thinning method for modelling the jump mechanism and combines the Euler-Maruyama scheme to approximate the underlying flow dynamics. For the proposed approximation schemes, we study both the mean-square and weak convergence. Weak convergence of the algorithms is established by a martingale problem formulation. Moreover, we employ these results to simulate the migration patterns exhibited by moving glioma cells at the microscopic level. Further, we develop and implement a splitting method for this PDifMP model and employ both the Thinned Euler-Maruyama and the splitting scheme in our simulation example, allowing us to compare both methods.
title Numerical Approximations and Convergence Analysis of Piecewise Diffusion Markov Processes, with Application to Glioma Cell Migration
topic Numerical Analysis
Probability
url https://arxiv.org/abs/2401.13428