npcure: An R Package for Nonparametric Inference in Mixture Cure Models
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arXiv
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| Main Authors: | , , |
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| Format: | Preprint |
| Published: |
2024
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| _version_ | 1866914659814080512 |
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| author | López-Cheda, Ana Jácome, M. Amalia López-de-Ullibarri, Ignacio |
| author_facet | López-Cheda, Ana Jácome, M. Amalia López-de-Ullibarri, Ignacio |
| contents | Mixture cure models have been widely used to analyze survival data with a cure fraction. They assume that a subgroup of the individuals under study will never experience the event (cured subjects). So, the goal is twofold: to study both the cure probability and the failure time of the uncured individuals through a proper survival function (latency). The R package npcure implements a completely nonparametric approach for estimating these functions in mixture cure models, considering right-censored survival times. Nonparametric estimators for the cure probability and the latency as functions of a covariate are provided. Bootstrap bandwidth selectors for the estimators are included. The package also implements a nonparametric covariate significance test for the cure probability, which can be applied with a continuous, discrete, or qualitative covariate. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2401_17346 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | npcure: An R Package for Nonparametric Inference in Mixture Cure Models López-Cheda, Ana Jácome, M. Amalia López-de-Ullibarri, Ignacio Methodology Mixture cure models have been widely used to analyze survival data with a cure fraction. They assume that a subgroup of the individuals under study will never experience the event (cured subjects). So, the goal is twofold: to study both the cure probability and the failure time of the uncured individuals through a proper survival function (latency). The R package npcure implements a completely nonparametric approach for estimating these functions in mixture cure models, considering right-censored survival times. Nonparametric estimators for the cure probability and the latency as functions of a covariate are provided. Bootstrap bandwidth selectors for the estimators are included. The package also implements a nonparametric covariate significance test for the cure probability, which can be applied with a continuous, discrete, or qualitative covariate. |
| title | npcure: An R Package for Nonparametric Inference in Mixture Cure Models |
| topic | Methodology |
| url | https://arxiv.org/abs/2401.17346 |