Prediction of multitasking performance post-longitudinal tDCS via EEG-based functional connectivity and machine learning methods

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Main Authors: Rao, Akash K, Uttrani, Shashank, Menon, Vishnu K, Shah, Darshil, Bhavsar, Arnav, Chowdhury, Shubhajit Roy, Dutt, Varun
Format: Preprint
Published: 2024
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author Rao, Akash K
Uttrani, Shashank
Menon, Vishnu K
Shah, Darshil
Bhavsar, Arnav
Chowdhury, Shubhajit Roy
Dutt, Varun
author_facet Rao, Akash K
Uttrani, Shashank
Menon, Vishnu K
Shah, Darshil
Bhavsar, Arnav
Chowdhury, Shubhajit Roy
Dutt, Varun
contents Predicting and understanding the changes in cognitive performance, especially after a longitudinal intervention, is a fundamental goal in neuroscience. Longitudinal brain stimulation-based interventions like transcranial direct current stimulation (tDCS) induce short-term changes in the resting membrane potential and influence cognitive processes. However, very little research has been conducted on predicting these changes in cognitive performance post-intervention. In this research, we intend to address this gap in the literature by employing different EEG-based functional connectivity analyses and machine learning algorithms to predict changes in cognitive performance in a complex multitasking task. Forty subjects were divided into experimental and active-control conditions. On Day 1, all subjects executed a multitasking task with simultaneous 32-channel EEG being acquired. From Day 2 to Day 7, subjects in the experimental condition undertook 15 minutes of 2mA anodal tDCS stimulation during task training. Subjects in the active-control condition undertook 15 minutes of sham stimulation during task training. On Day 10, all subjects again executed the multitasking task with EEG acquisition. Source-level functional connectivity metrics, namely phase lag index and directed transfer function, were extracted from the EEG data on Day 1 and Day 10. Various machine learning models were employed to predict changes in cognitive performance. Results revealed that the multi-layer perceptron and directed transfer function recorded a cross-validation training RMSE of 5.11% and a test RMSE of 4.97%. We discuss the implications of our results in developing real-time cognitive state assessors for accurately predicting cognitive performance in dynamic and complex tasks post-tDCS intervention
format Preprint
id arxiv_https___arxiv_org_abs_2401_17711
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Prediction of multitasking performance post-longitudinal tDCS via EEG-based functional connectivity and machine learning methods
Rao, Akash K
Uttrani, Shashank
Menon, Vishnu K
Shah, Darshil
Bhavsar, Arnav
Chowdhury, Shubhajit Roy
Dutt, Varun
Human-Computer Interaction
Artificial Intelligence
Predicting and understanding the changes in cognitive performance, especially after a longitudinal intervention, is a fundamental goal in neuroscience. Longitudinal brain stimulation-based interventions like transcranial direct current stimulation (tDCS) induce short-term changes in the resting membrane potential and influence cognitive processes. However, very little research has been conducted on predicting these changes in cognitive performance post-intervention. In this research, we intend to address this gap in the literature by employing different EEG-based functional connectivity analyses and machine learning algorithms to predict changes in cognitive performance in a complex multitasking task. Forty subjects were divided into experimental and active-control conditions. On Day 1, all subjects executed a multitasking task with simultaneous 32-channel EEG being acquired. From Day 2 to Day 7, subjects in the experimental condition undertook 15 minutes of 2mA anodal tDCS stimulation during task training. Subjects in the active-control condition undertook 15 minutes of sham stimulation during task training. On Day 10, all subjects again executed the multitasking task with EEG acquisition. Source-level functional connectivity metrics, namely phase lag index and directed transfer function, were extracted from the EEG data on Day 1 and Day 10. Various machine learning models were employed to predict changes in cognitive performance. Results revealed that the multi-layer perceptron and directed transfer function recorded a cross-validation training RMSE of 5.11% and a test RMSE of 4.97%. We discuss the implications of our results in developing real-time cognitive state assessors for accurately predicting cognitive performance in dynamic and complex tasks post-tDCS intervention
title Prediction of multitasking performance post-longitudinal tDCS via EEG-based functional connectivity and machine learning methods
topic Human-Computer Interaction
Artificial Intelligence
url https://arxiv.org/abs/2401.17711