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Autori principali: Vetter, Roman, Iber, Dagmar
Natura: Preprint
Pubblicazione: 2024
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Accesso online:https://arxiv.org/abs/2402.00781
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author Vetter, Roman
Iber, Dagmar
author_facet Vetter, Roman
Iber, Dagmar
contents In a recent article [Vetter and Iber, Nat. Commun. 13, 1145 (2022)], we demonstrated that single morphogen gradients in the developing mouse neural tube can carry sufficient positional accuracy to explain the patterning precision of progenitor domain boundaries. Zagorski et al. had previously concluded otherwise [Zagorski et al., Science 356, 1379-1383 (2017)], based on methodological inconsistencies that we have revealed. The authors now comment on our work with a Matters Arising letter. We rebut their criticism point by point in the Supplement, and summarize the main aspects here.
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publishDate 2024
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spellingShingle Reply to: Assessing the precision of morphogen gradients in neural tube development
Vetter, Roman
Iber, Dagmar
Biological Physics
In a recent article [Vetter and Iber, Nat. Commun. 13, 1145 (2022)], we demonstrated that single morphogen gradients in the developing mouse neural tube can carry sufficient positional accuracy to explain the patterning precision of progenitor domain boundaries. Zagorski et al. had previously concluded otherwise [Zagorski et al., Science 356, 1379-1383 (2017)], based on methodological inconsistencies that we have revealed. The authors now comment on our work with a Matters Arising letter. We rebut their criticism point by point in the Supplement, and summarize the main aspects here.
title Reply to: Assessing the precision of morphogen gradients in neural tube development
topic Biological Physics
url https://arxiv.org/abs/2402.00781