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Bibliographic Details
Main Authors: Blom, Erik, Engblom, Stefan, Menz, Gesina
Format: Preprint
Published: 2024
Subjects:
Online Access:https://arxiv.org/abs/2402.01305
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Table of Contents:
  • We present a stochastic computational model of avascular tumors, emphasizing the detailed implementation of the first four so-called hallmarks of cancer: self-sufficiency in growth factors, resistance to growth inhibitors, avoidance of apoptosis, and unlimited growth potential. Our goal is to provide a foundational understanding of the first steps of cancer malignancy while addressing modeling uncertainties, thus bringing us closer to a first-principles grasp of this process. Preliminary numerical simulations illustrate the comprehensiveness of our perspective.