CEHR-GPT: Generating Electronic Health Records with Chronological Patient Timelines

Fuente: arXiv
Saved in:
Bibliographic Details
Main Authors: Pang, Chao, Jiang, Xinzhuo, Pavinkurve, Nishanth Parameshwar, Kalluri, Krishna S., Minto, Elise L., Patterson, Jason, Zhang, Linying, Hripcsak, George, Gürsoy, Gamze, Elhadad, Noémie, Natarajan, Karthik
Format: Preprint
Published: 2024
Subjects:
Online Access:
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1866913342218567680
author Pang, Chao
Jiang, Xinzhuo
Pavinkurve, Nishanth Parameshwar
Kalluri, Krishna S.
Minto, Elise L.
Patterson, Jason
Zhang, Linying
Hripcsak, George
Gürsoy, Gamze
Elhadad, Noémie
Natarajan, Karthik
author_facet Pang, Chao
Jiang, Xinzhuo
Pavinkurve, Nishanth Parameshwar
Kalluri, Krishna S.
Minto, Elise L.
Patterson, Jason
Zhang, Linying
Hripcsak, George
Gürsoy, Gamze
Elhadad, Noémie
Natarajan, Karthik
contents Synthetic Electronic Health Records (EHR) have emerged as a pivotal tool in advancing healthcare applications and machine learning models, particularly for researchers without direct access to healthcare data. Although existing methods, like rule-based approaches and generative adversarial networks (GANs), generate synthetic data that resembles real-world EHR data, these methods often use a tabular format, disregarding temporal dependencies in patient histories and limiting data replication. Recently, there has been a growing interest in leveraging Generative Pre-trained Transformers (GPT) for EHR data. This enables applications like disease progression analysis, population estimation, counterfactual reasoning, and synthetic data generation. In this work, we focus on synthetic data generation and demonstrate the capability of training a GPT model using a particular patient representation derived from CEHR-BERT, enabling us to generate patient sequences that can be seamlessly converted to the Observational Medical Outcomes Partnership (OMOP) data format.
format Preprint
id arxiv_https___arxiv_org_abs_2402_04400
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle CEHR-GPT: Generating Electronic Health Records with Chronological Patient Timelines
Pang, Chao
Jiang, Xinzhuo
Pavinkurve, Nishanth Parameshwar
Kalluri, Krishna S.
Minto, Elise L.
Patterson, Jason
Zhang, Linying
Hripcsak, George
Gürsoy, Gamze
Elhadad, Noémie
Natarajan, Karthik
Machine Learning
Artificial Intelligence
Computers and Society
Synthetic Electronic Health Records (EHR) have emerged as a pivotal tool in advancing healthcare applications and machine learning models, particularly for researchers without direct access to healthcare data. Although existing methods, like rule-based approaches and generative adversarial networks (GANs), generate synthetic data that resembles real-world EHR data, these methods often use a tabular format, disregarding temporal dependencies in patient histories and limiting data replication. Recently, there has been a growing interest in leveraging Generative Pre-trained Transformers (GPT) for EHR data. This enables applications like disease progression analysis, population estimation, counterfactual reasoning, and synthetic data generation. In this work, we focus on synthetic data generation and demonstrate the capability of training a GPT model using a particular patient representation derived from CEHR-BERT, enabling us to generate patient sequences that can be seamlessly converted to the Observational Medical Outcomes Partnership (OMOP) data format.
title CEHR-GPT: Generating Electronic Health Records with Chronological Patient Timelines
topic Machine Learning
Artificial Intelligence
Computers and Society
url https://arxiv.org/abs/2402.04400