Determining the severity of Parkinson's disease in patients using a multi task neural network

Fuente: arXiv
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Main Authors: García-Ordás, María Teresa, Benítez-Andrades, José Alberto, Aveleira-Mata, Jose, Alija-Pérez, José-Manuel, Benavides, Carmen
Format: Preprint
Published: 2024
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author García-Ordás, María Teresa
Benítez-Andrades, José Alberto
Aveleira-Mata, Jose
Alija-Pérez, José-Manuel
Benavides, Carmen
author_facet García-Ordás, María Teresa
Benítez-Andrades, José Alberto
Aveleira-Mata, Jose
Alija-Pérez, José-Manuel
Benavides, Carmen
contents Parkinson's disease is easy to diagnose when it is advanced, but it is very difficult to diagnose in its early stages. Early diagnosis is essential to be able to treat the symptoms. It impacts on daily activities and reduces the quality of life of both the patients and their families and it is also the second most prevalent neurodegenerative disorder after Alzheimer in people over the age of 60. Most current studies on the prediction of Parkinson's severity are carried out in advanced stages of the disease. In this work, the study analyzes a set of variables that can be easily extracted from voice analysis, making it a very non-intrusive technique. In this paper, a method based on different deep learning techniques is proposed with two purposes. On the one hand, to find out if a person has severe or non-severe Parkinson's disease, and on the other hand, to determine by means of regression techniques the degree of evolution of the disease in a given patient. The UPDRS (Unified Parkinson's Disease Rating Scale) has been used by taking into account both the motor and total labels, and the best results have been obtained using a mixed multi-layer perceptron (MLP) that classifies and regresses at the same time and the most important features of the data obtained are taken as input, using an autoencoder. A success rate of 99.15% has been achieved in the problem of predicting whether a person suffers from severe Parkinson's disease or non-severe Parkinson's disease. In the degree of disease involvement prediction problem case, a MSE (Mean Squared Error) of 0.15 has been obtained. Using a full deep learning pipeline for data preprocessing and classification has proven to be very promising in the field Parkinson's outperforming the state-of-the-art proposals.
format Preprint
id arxiv_https___arxiv_org_abs_2402_05491
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Determining the severity of Parkinson's disease in patients using a multi task neural network
García-Ordás, María Teresa
Benítez-Andrades, José Alberto
Aveleira-Mata, Jose
Alija-Pérez, José-Manuel
Benavides, Carmen
Machine Learning
Sound
Audio and Speech Processing
Parkinson's disease is easy to diagnose when it is advanced, but it is very difficult to diagnose in its early stages. Early diagnosis is essential to be able to treat the symptoms. It impacts on daily activities and reduces the quality of life of both the patients and their families and it is also the second most prevalent neurodegenerative disorder after Alzheimer in people over the age of 60. Most current studies on the prediction of Parkinson's severity are carried out in advanced stages of the disease. In this work, the study analyzes a set of variables that can be easily extracted from voice analysis, making it a very non-intrusive technique. In this paper, a method based on different deep learning techniques is proposed with two purposes. On the one hand, to find out if a person has severe or non-severe Parkinson's disease, and on the other hand, to determine by means of regression techniques the degree of evolution of the disease in a given patient. The UPDRS (Unified Parkinson's Disease Rating Scale) has been used by taking into account both the motor and total labels, and the best results have been obtained using a mixed multi-layer perceptron (MLP) that classifies and regresses at the same time and the most important features of the data obtained are taken as input, using an autoencoder. A success rate of 99.15% has been achieved in the problem of predicting whether a person suffers from severe Parkinson's disease or non-severe Parkinson's disease. In the degree of disease involvement prediction problem case, a MSE (Mean Squared Error) of 0.15 has been obtained. Using a full deep learning pipeline for data preprocessing and classification has proven to be very promising in the field Parkinson's outperforming the state-of-the-art proposals.
title Determining the severity of Parkinson's disease in patients using a multi task neural network
topic Machine Learning
Sound
Audio and Speech Processing
url https://arxiv.org/abs/2402.05491