Brief overview on Bacteriophage therapy; Alternative to Antibiotics

Fuente: arXiv
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Main Authors: Atique, Rameen, Saeed, Hafiza Arshi, Anwar, Bushra, Rana, Tehreem, Haidar, Ayesha, Muazzam, Ayesha, Naveed, Areesha, Sharif, Javeria, Perveen, Aqsa, Fatima, Hafiza Rida, Samad, Abdul
Format: Preprint
Published: 2024
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author Atique, Rameen
Saeed, Hafiza Arshi
Anwar, Bushra
Rana, Tehreem
Haidar, Ayesha
Muazzam, Ayesha
Naveed, Areesha
Sharif, Javeria
Perveen, Aqsa
Fatima, Hafiza Rida
Samad, Abdul
author_facet Atique, Rameen
Saeed, Hafiza Arshi
Anwar, Bushra
Rana, Tehreem
Haidar, Ayesha
Muazzam, Ayesha
Naveed, Areesha
Sharif, Javeria
Perveen, Aqsa
Fatima, Hafiza Rida
Samad, Abdul
contents The term bacteriophage means killer or eater of bacteria. They were initially discovered by F.W. Twort and later on, Felix d'Herelle unveiled them to the world in 1910. Phage therapy has arisen as a favorable option to conventional antibiotics by reducing the multinational problem of increasing antibacterial resistance. These virulent viruses particularly prey on and contaminate bacterial strains and aid in fighting bacterial diseases. Researchers are performing various clinical trials on the bacteriophage to tackle pathogenic bacterial infections, varying from typical illnesses to highly invulnerable biofilms that cannot be treated with antibiotics. The primary experiments demonstrated that phage therapy has fewer consequences than traditional antimicrobial drugs. It is safer to use and show results within a few days. Although phage therapy has a wide range of promising results, but it also encounters diverse obstacles. One is that they are host-specific and can merely be used for personalized therapy. As thousands of bacteria can cause disease, clinicians have to construct a library of phage viruses. For successful treatment, an analysis of versatility, stability, and immune interference related to bacteriophage is necessary. Phage therapy is an excellent substitute for antibiotics as it illustrates a living base for the treatment of infections and it is climate-friendly. It only targets the pathogenic cells and has less influence on the normal microbiota. Regardless of the challenges and problems, phage therapy is approved as a beneficial approach to combating contagious infections.
format Preprint
id arxiv_https___arxiv_org_abs_2402_10245
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Brief overview on Bacteriophage therapy; Alternative to Antibiotics
Atique, Rameen
Saeed, Hafiza Arshi
Anwar, Bushra
Rana, Tehreem
Haidar, Ayesha
Muazzam, Ayesha
Naveed, Areesha
Sharif, Javeria
Perveen, Aqsa
Fatima, Hafiza Rida
Samad, Abdul
Other Quantitative Biology
The term bacteriophage means killer or eater of bacteria. They were initially discovered by F.W. Twort and later on, Felix d'Herelle unveiled them to the world in 1910. Phage therapy has arisen as a favorable option to conventional antibiotics by reducing the multinational problem of increasing antibacterial resistance. These virulent viruses particularly prey on and contaminate bacterial strains and aid in fighting bacterial diseases. Researchers are performing various clinical trials on the bacteriophage to tackle pathogenic bacterial infections, varying from typical illnesses to highly invulnerable biofilms that cannot be treated with antibiotics. The primary experiments demonstrated that phage therapy has fewer consequences than traditional antimicrobial drugs. It is safer to use and show results within a few days. Although phage therapy has a wide range of promising results, but it also encounters diverse obstacles. One is that they are host-specific and can merely be used for personalized therapy. As thousands of bacteria can cause disease, clinicians have to construct a library of phage viruses. For successful treatment, an analysis of versatility, stability, and immune interference related to bacteriophage is necessary. Phage therapy is an excellent substitute for antibiotics as it illustrates a living base for the treatment of infections and it is climate-friendly. It only targets the pathogenic cells and has less influence on the normal microbiota. Regardless of the challenges and problems, phage therapy is approved as a beneficial approach to combating contagious infections.
title Brief overview on Bacteriophage therapy; Alternative to Antibiotics
topic Other Quantitative Biology
url https://arxiv.org/abs/2402.10245