Toward a Team of AI-made Scientists for Scientific Discovery from Gene Expression Data

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Hauptverfasser: Liu, Haoyang, Li, Yijiang, Jian, Jinglin, Cheng, Yuxuan, Lu, Jianrong, Guo, Shuyi, Zhu, Jinglei, Zhang, Mianchen, Zhang, Miantong, Wang, Haohan
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Veröffentlicht: 2024
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author Liu, Haoyang
Li, Yijiang
Jian, Jinglin
Cheng, Yuxuan
Lu, Jianrong
Guo, Shuyi
Zhu, Jinglei
Zhang, Mianchen
Zhang, Miantong
Wang, Haohan
author_facet Liu, Haoyang
Li, Yijiang
Jian, Jinglin
Cheng, Yuxuan
Lu, Jianrong
Guo, Shuyi
Zhu, Jinglei
Zhang, Mianchen
Zhang, Miantong
Wang, Haohan
contents Machine learning has emerged as a powerful tool for scientific discovery, enabling researchers to extract meaningful insights from complex datasets. For instance, it has facilitated the identification of disease-predictive genes from gene expression data, significantly advancing healthcare. However, the traditional process for analyzing such datasets demands substantial human effort and expertise for the data selection, processing, and analysis. To address this challenge, we introduce a novel framework, a Team of AI-made Scientists (TAIS), designed to streamline the scientific discovery pipeline. TAIS comprises simulated roles, including a project manager, data engineer, and domain expert, each represented by a Large Language Model (LLM). These roles collaborate to replicate the tasks typically performed by data scientists, with a specific focus on identifying disease-predictive genes. Furthermore, we have curated a benchmark dataset to assess TAIS's effectiveness in gene identification, demonstrating our system's potential to significantly enhance the efficiency and scope of scientific exploration. Our findings represent a solid step towards automating scientific discovery through large language models.
format Preprint
id arxiv_https___arxiv_org_abs_2402_12391
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Toward a Team of AI-made Scientists for Scientific Discovery from Gene Expression Data
Liu, Haoyang
Li, Yijiang
Jian, Jinglin
Cheng, Yuxuan
Lu, Jianrong
Guo, Shuyi
Zhu, Jinglei
Zhang, Mianchen
Zhang, Miantong
Wang, Haohan
Genomics
Artificial Intelligence
Machine Learning
Machine learning has emerged as a powerful tool for scientific discovery, enabling researchers to extract meaningful insights from complex datasets. For instance, it has facilitated the identification of disease-predictive genes from gene expression data, significantly advancing healthcare. However, the traditional process for analyzing such datasets demands substantial human effort and expertise for the data selection, processing, and analysis. To address this challenge, we introduce a novel framework, a Team of AI-made Scientists (TAIS), designed to streamline the scientific discovery pipeline. TAIS comprises simulated roles, including a project manager, data engineer, and domain expert, each represented by a Large Language Model (LLM). These roles collaborate to replicate the tasks typically performed by data scientists, with a specific focus on identifying disease-predictive genes. Furthermore, we have curated a benchmark dataset to assess TAIS's effectiveness in gene identification, demonstrating our system's potential to significantly enhance the efficiency and scope of scientific exploration. Our findings represent a solid step towards automating scientific discovery through large language models.
title Toward a Team of AI-made Scientists for Scientific Discovery from Gene Expression Data
topic Genomics
Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2402.12391