scInterpreter: Training Large Language Models to Interpret scRNA-seq Data for Cell Type Annotation

Fuente: arXiv
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Autori principali: Li, Cong, Xiao, Meng, Wang, Pengfei, Feng, Guihai, Li, Xin, Zhou, Yuanchun
Natura: Preprint
Pubblicazione: 2024
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author Li, Cong
Xiao, Meng
Wang, Pengfei
Feng, Guihai
Li, Xin
Zhou, Yuanchun
author_facet Li, Cong
Xiao, Meng
Wang, Pengfei
Feng, Guihai
Li, Xin
Zhou, Yuanchun
contents Despite the inherent limitations of existing Large Language Models in directly reading and interpreting single-cell omics data, they demonstrate significant potential and flexibility as the Foundation Model. This research focuses on how to train and adapt the Large Language Model with the capability to interpret and distinguish cell types in single-cell RNA sequencing data. Our preliminary research results indicate that these foundational models excel in accurately categorizing known cell types, demonstrating the potential of the Large Language Models as effective tools for uncovering new biological insights.
format Preprint
id arxiv_https___arxiv_org_abs_2402_12405
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle scInterpreter: Training Large Language Models to Interpret scRNA-seq Data for Cell Type Annotation
Li, Cong
Xiao, Meng
Wang, Pengfei
Feng, Guihai
Li, Xin
Zhou, Yuanchun
Genomics
Artificial Intelligence
Despite the inherent limitations of existing Large Language Models in directly reading and interpreting single-cell omics data, they demonstrate significant potential and flexibility as the Foundation Model. This research focuses on how to train and adapt the Large Language Model with the capability to interpret and distinguish cell types in single-cell RNA sequencing data. Our preliminary research results indicate that these foundational models excel in accurately categorizing known cell types, demonstrating the potential of the Large Language Models as effective tools for uncovering new biological insights.
title scInterpreter: Training Large Language Models to Interpret scRNA-seq Data for Cell Type Annotation
topic Genomics
Artificial Intelligence
url https://arxiv.org/abs/2402.12405